FB2024_03 , released June 25, 2024
Allele: Dmel\fizKK103055
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General Information
Symbol
Dmel\fizKK103055
Species
D. melanogaster
Name
FlyBase ID
FBal0232165
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Transgenic product class
Nature of the Allele
Transgenic product class
Progenitor genotype
Carried in construct
Cytology
Description

UASt regulatory sequences drive expression of an inverted repeat.

Allele components
Component
Use(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

The expression of fizKK103055 under the control of Scer\GAL4Act5C.PU leads to significantly decreased tolerance to DDT and Malathion, but not to Ethanol, in both females and males (assessed by Mortality upon exposure), and to a significantly decreased cold tolerance in females only (assessed as the recovery time from chill coma), as compared to controls; this expression also leads to significant increases in larval volume, adult weight, adult wing length (males and females) and area (female only), as well as in adult wing loading, as compared to controls.

Expression of CG9509KK103055 under the control of Scer\GAL4Abd-B.D1 results in aberrant morphology (multiple small vacuoles that appear to be interconnected) of the secondary cells in male accessory glands. Wild-type mates of these knock-down males lay fewer eggs and display defects in post-mating receptivity suppression - the females become receptive for re-mating sooner (by 4 days after start of mating) than when mated with wild-type males.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
CG9509KK103055
fizKK103055
Name Synonyms
Secondary FlyBase IDs
    References (4)