FlyBase Allele Report: Dmel\hui[KK112899]

General Information

Symbol

Dmel\hui^KK112899

Species

D. melanogaster

Name

FlyBase ID

FBal0238472

Feature type

allele

Associated gene

Dmel\hui

Associated Insertion(s)

Carried in Construct

P{KK112899}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

(Keleman et al., 2009.8.5)

Progenitor genotype

Carried in construct

P{KK112899}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-KK112899

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal, with Scer\GAL4^Act5C.PU

(Butchar et al., 2012)

visible | adult stage, with Scer\GAL4^C-765

(Ibrahim et al., 2013)

visible | adult stage, with Scer\GAL4^en-e16E

(Ibrahim et al., 2013)

visible | adult stage, with Scer\GAL4^ptc-559.1

(Ibrahim et al., 2013)

Phenotype Manifest In

anterior crossvein, with Scer\GAL4^C-765

(Ibrahim et al., 2013)

wing | posterior, with Scer\GAL4^en-e16E

(Ibrahim et al., 2013)

wing margin bristle, with Scer\GAL4^en-e16E

(Ibrahim et al., 2013)

wing vein L3, with Scer\GAL4^C-765

(Ibrahim et al., 2013)

wing vein L3, with Scer\GAL4^ptc-559.1

(Ibrahim et al., 2013)

wing vein L4, with Scer\GAL4^C-765

(Ibrahim et al., 2013)

wing vein L4, with Scer\GAL4^ptc-559.1

(Ibrahim et al., 2013)

Detailed Description

Statement

Reference

Expression of hui^KK112899 under the control of Scer\GAL4^ptc-559.1 results in stubby wings, narrows the L3-L4 intervein region and reduces the anterior crossvein. Gaps in L3 are also seen. Expression throughout the wing using Scer\GAL4^C-765 results in small wings and causes L3-L4 malformation and occasional partial ablation of the anterior crossvein. A small posterior compartment is seen when hui^KK112899 is expressed under the control of Scer\GAL4^en-e16E. The L3-L4 intervein region is not reduced and the anterior crossvein is present. However the phasing of the bristles at the posterior wing margin is disturbed.

(Ibrahim et al., 2013)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v103328

P{KK112899}VIE-260B

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

CG10200^KK112899

hui^KK112899

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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