FB2024_03 , released June 25, 2024
Allele: Dmel\Ilp6VDRC.cUa
Open Close
General Information
Symbol
Dmel\Ilp6VDRC.cUa
Species
D. melanogaster
Name
FlyBase ID
FBal0241438
Feature type
allele
Associated gene
Dmel\Ilp6
Associated Insertion(s)
Carried in Construct
P{VDRC.Ilp6.U}
Key Links
Transgenic product class
RNAi_reagent
(Slaidina et al., 2009)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Slaidina et al., 2009)
Mutagen
in vitro construct
(Slaidina et al., 2009)
Progenitor genotype
Carried in construct
P{VDRC.Ilp6.U}
Cytology
Description

UAS regulatory sequences drive expression of an inverted repeat.

(Slaidina et al., 2009)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Ilp6
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Adults in which expression of Ilp6VDRC.cUa under the control of Scer\GAL4Act occurs up to 96 hours after egg deposition (AED) have a normal mass. However, animals in which which expression of Ilp6VDRC.cUa under the control of Scer\GAL4Act occurs up to 120 hours AED have a reduced mass compared to control animals. Adults in which Ilp6GD3987 has been expressed under the control of Scer\GAL4Act from 120 hours AED until adult emergence show increased resistance to starvation compared to controls. The adults have increased levels of glycogen and triacylglycerides compared to controls. (In all these experiments, the temperature sensitive Scer\GAL80ts.αTub84B allele has been used to control the activity of the Scer\GAL4 driver).

      (Slaidina et al., 2009)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Ilp6VDRC.cUa
      Name Synonyms
      Secondary FlyBase IDs
        References (1)