FlyBase Allele Report: Dmel\Imp[SD.UASp]

General Information

Symbol

Dmel\Imp^SD.UASp

Species

D. melanogaster

Name

FlyBase ID

FBal0241639

Feature type

allele

Associated gene

Dmel\Imp

Associated Insertion(s)

Carried in Construct

P{UASp-Imp.SD}

Key Links

Transgenic product class

cDNA

(Boylan et al., 2008)

wild_type

(Boylan et al., 2008)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

cDNA

(Boylan et al., 2008)

wild_type

(Boylan et al., 2008)

Mutagen

in vitro construct

(Boylan et al., 2008)

Progenitor genotype

Carried in construct

P{UASp-Imp.SD}

Cytology

Description

UAS regulatory sequences drive expression of Imp cDNA SD07045.

(Boylan et al., 2008)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Imp

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy, with Scer\GAL4^ppk.PG

(Hattori et al., 2013)

lethal - all die before end of P-stage, with Scer\GAL4^Act5C.PU

(Boylan et al., 2008)

lethal - all die during embryonic stage, with Scer\GAL4^{VP16.mat.αTub67C}

(Boylan et al., 2008)

some die during embryonic stage, with Scer\GAL4^{VP16.mat.αTub67C}

(Boylan et al., 2008)

some die during pharate adult stage, with Scer\GAL4^Act5C.PU

(Boylan et al., 2008)

viable, with Scer\GAL4^elav.PU

(Boylan et al., 2008)

Phenotype Manifest In

abdominal dorsal multidendritic neuron ddaC | third instar larval stage, with Scer\GAL4^ppk.PG

(Hattori et al., 2013)

dendritic tree | third instar larval stage, with Scer\GAL4^ppk.PG

(Hattori et al., 2013)

dorsal appendage, with Scer\GAL4^{VP16.mat.αTub67C}

(Boylan et al., 2008)

Detailed Description

Statement

Reference

Third instar larval class IV abdominal dorsal multidendritic ddaC neurons expressing Imp^SD.Scer\UAS under the control of Scer\GAL4^ppk.PG present a significant increase in the number of dendrite branch terminals, as compared to controls; expression under the control of Scer\GAL4²²¹ results in no obvious dendrite morphology defects in class I abdominal dorsal multidendritic ddaD and ddaE neurons, as compared to controls.

(Hattori et al., 2013)

Expression of Imp^SD.Scer\UAS under the control of Scer\GAL4^{mat.αTub67C.T:Hsim\VP16} results in a fused dorsal appendage phenotype and the animals fail to hatch (the penetrance of this phenotype varies from 29% to 47%).

Expression of Imp^SD.Scer\UAS under the control of Scer\GAL4^elav.PU has no effect on synaptic terminal size at the larval neuromuscular junction.

(Boylan et al., 2008)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Imp^SD.Scer\UAS

Imp^SD.UASp

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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