FB2024_03 , released June 25, 2024
Allele: Dmel\ShawRNAi.Sym.UAS
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General Information
Symbol
Dmel\ShawRNAi.Sym.UAS
Species
D. melanogaster
Name
Sense construct of Parisky
FlyBase ID
FBal0244814
Feature type
allele
Associated gene
Dmel\Shaw
Associated Insertion(s)
Carried in Construct
P{Sym-UAS-Shaw}
Key Links
Transgenic product class
RNAi_reagent
(Parisky et al., 2008)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Parisky et al., 2008)
Mutagen
in vitro construct
(Parisky et al., 2008)
Progenitor genotype
Carried in construct
P{Sym-UAS-Shaw}
Cytology
Description

Sense-antisense transcription of a 720bp Shaw fragment (driven by two convergent arrays of UAS sequence) results in double stranded RNA (dsRNA) expression.

(Parisky et al., 2008)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Shaw
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of P{Sym-UAS-Shaw} using Scer\GAL4C380 increases the resting membrane potential and the fire-rate response of larval motor neurons. Expression of P{Sym-UAS-Shaw} with Scer\GAL4P2.4.Pdf results in a reduction in total sleep during the day and night, but a significant increase in sleep latency only during lights-off, compared to controls.

      (Parisky et al., 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments

      Expression of ShawdsRNA.Sym.Scer\UAS using Scer\GAL4C380 increases the resting membrane potential and the fire-rate response of larval motor neurons.

      Expression of ShawdsRNA.Sym.Scer\UAS with Scer\GAL4P2.4.Pdf results in a reduction in total sleep during the day and night, but a significant increase in sleep latency only during lights-off, compared to controls.

      (Parisky et al., 2008)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Associated with: Shaw[a.Sym.Scer\UAS]

      (Parisky et al., 2008)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      ShawRNAi.Sym.UAS
      ShawSym.Scer\UAS
      ShawdsRNA.Sym.Scer\UAS
      ShawdsRNA.Sym.UAS
      Name Synonyms
      Sense construct of Parisky
      Secondary FlyBase IDs
      • FBal0244813
      References (3)