FB2024_03 , released June 25, 2024
Allele: Dmel\HΔGC.UAS
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General Information
Symbol
Dmel\HΔGC.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0246338
Feature type
allele
Associated gene
Dmel\H
Associated Insertion(s)
Carried in Construct
P{UAS-H.ΔGC}
Key Links
Transgenic product class
inframe_deletion
(Nagel et al., 2005)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Nagel et al., 2005)
Mutagen
in vitro construct
(Nagel et al., 2005)
Progenitor genotype
Carried in construct
P{UAS-H.ΔGC}
Cytology
Description

UAS regulatory sequences drive expression of a modified form of H, lacking amino acids 490-712 and 1062-1076.

(Nagel et al., 2005)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
H
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of HΔGC.Scer\UAS under the control of Scer\GAL4bi-md653 in the wing causes wing margin loss and notching, and thickened veins.

      (Nagel et al., 2005)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Other
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of HΔC.Scer\UAS and Su(H)Scer\UAS.cNa in the wing under the control of Scer\GAL4bi-md653 results in viable offspring with a strongly enhanced wing phenotype compared with expression of HΔC.Scer\UAS alone. Supernumerary bristles are observed along thickened veins.

      (Nagel et al., 2005)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      HΔGC.Scer\UAS
      HΔGC.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (1)