FlyBase Allele Report: Scer\GAL4[GMR61G12]

General Information

Symbol

Scer\GAL4^GMR61G12

Species

S. cerevisiae

Name

FlyBase ID

FBal0256531

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

Carried in Construct

P{GMR61G12-GAL4}

Also Known As

R61G12, pdf-Gal4

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Pfeiffer et al., 2011.2.9)

Progenitor genotype

Carried in construct

P{GMR61G12-GAL4}

Cytology

Description

A 1152 base pair fragment from the Pdf region, including the putative endogenous Pdf promoter, is fused upstream of sequence encoding a GAL4 driver.

(Pfeiffer et al., 2011.2.9)

Allele components

Component

Use(s)

Regulatory region(s)

GMR61G12

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

wandering third instar larval stage

adult s-LNv neuron | subset

(Li et al., 2014)

adult stage

adult pacemaker neuron

(Kunst et al., 2014)

adult s-LNv neuron | subset

(Sekiguchi et al., 2020, Li et al., 2014)

l-LNv neuron | subset

(Sekiguchi et al., 2020)

Additional Information

Statement

Reference

Marker for

Reflects expression of

Pdf

(Kunst et al., 2014)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy | adult stage | progressive, with Hsap\HTT^{Q72.ex1.UAS.cWa}

(Wen et al., 2020)

abnormal neuroanatomy | adult stage | progressive, with Zzzz\GGGGCC^30.UAS.EGFP

(Wen et al., 2020)

Phenotype Manifest In

adult s-LNv neuron | adult stage, with Hsap\HTT^{Q72.ex1.UAS.cWa}

(Wen et al., 2020)

adult s-LNv neuron | adult stage, with Zzzz\GGGGCC^30.UAS.EGFP

(Wen et al., 2020)

axon | adult stage, with Hsap\HTT^{Q72.ex1.UAS.cWa}

(Wen et al., 2020)

axon | adult stage, with Zzzz\GGGGCC^30.UAS.EGFP

(Wen et al., 2020)

dendrite | adult stage, with Hsap\HTT^{Q72.ex1.UAS.cWa}

(Wen et al., 2020)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Hsap\HTT^{Q72.ex1.UAS.cWa}, Scer\GAL4^GMR61G12 has abnormal neuroanatomy | adult stage phenotype, suppressible | partially by tau^KO/tau^KO

(Wen et al., 2020)

Scer\GAL4^GMR61G12, Zzzz\GGGGCC^30.UAS.EGFP has abnormal neuroanatomy | adult stage | progressive phenotype, suppressible | partially by tau^KO/tau^KO

(Wen et al., 2020)

Phenotype Manifest In

Suppressed by

Statement

Reference

Hsap\HTT^{Q72.ex1.UAS.cWa}, Scer\GAL4^GMR61G12 has axon | adult stage phenotype, suppressible | partially by tau^KO/tau^KO

(Wen et al., 2020)

Hsap\HTT^{Q72.ex1.UAS.cWa}, Scer\GAL4^GMR61G12 has adult s-LNv neuron | adult stage phenotype, suppressible | partially by tau^KO/tau^KO

(Wen et al., 2020)

Scer\GAL4^GMR61G12, Zzzz\GGGGCC^30.UAS.EGFP has axon | adult stage phenotype, suppressible | partially by tau^KO/tau^KO

(Wen et al., 2020)

Scer\GAL4^GMR61G12, Zzzz\GGGGCC^30.UAS.EGFP has adult s-LNv neuron | adult stage phenotype, suppressible | partially by tau^KO/tau^KO

(Wen et al., 2020)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

41286

w¹¹¹⁸; P{GMR61G12-GAL4}attP2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Scer\GAL4^GMR61G12

Name Synonyms

Secondary FlyBase IDs

References (12)

Report Sections

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