FB2024_03 , released June 25, 2024
Allele: Dmel\ninaEAAXXA
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General Information
Symbol
Dmel\ninaEAAXXA
Species
D. melanogaster
Name
FlyBase ID
FBal0260591
Feature type
allele
Associated gene
Dmel\ninaE
Associated Insertion(s)
Carried in Construct
P{ninaE-Rh1.AAXXA}
Key Links
Transgenic product class
missense_variant
(Pinal and Pichaud, 2011)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Pinal and Pichaud, 2011)
Mutagen
in vitro construct
(Pinal and Pichaud, 2011)
Progenitor genotype
Carried in construct
P{ninaE-Rh1.AAXXA}
Cytology
Description

The minimal ninaE promoter drives expression of ninaE, which contains the mutations N325A, P326A and Y329A in the NPxxY motif.

(Pinal and Pichaud, 2011)
Allele components
Component
Use(s)
Regulatory region(s)
ninaE
Encoded product / tool
ninaE
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      ninaEAAXXA partially rescues ninaE17

      (Pinal and Pichaud, 2011)
      Comments

      ninaEAAXXA significantly rescues the collapsing of the closely apposed membrane inside the cells that is seen in ninaE17 photoreceptors. However, there are numerous vesicles occupying the sub-rhabdomeric space.

      (Pinal and Pichaud, 2011)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      ninaEAAXXA
      Name Synonyms
      Secondary FlyBase IDs
        References (1)