FB2024_03 , released June 25, 2024
Allele: Dmel\qsmRNAi.UAS
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General Information
Symbol
Dmel\qsmRNAi.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0260603
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
uas-qsmRNAi(2)
Key Links
Transgenic product class
Nature of the Allele
Transgenic product class
Progenitor genotype
Carried in construct
Cytology
Description

UAS regulatory sequences drive expression of a qsm RNAi construct.

Allele components
Component
Use(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Flies expressing qsmdsRNA.Scer\UAS under the control of Scer\GAL4tim.PE exhibit robust, long-period locomotor rhythms in constant dim white light, in contrast to control flies which largely show arrhythmic behavior in these conditions.

Under bright (2500 lux) constant light conditions, between 50 and 85% of flies expressing qsmdsRNA.Scer\UAS under the control of Scer\GAL4tim.PE show robust locomotor activity rhythmicity, with an average period length of 27.2 hours.

Under dim (35-55 lux) constant light conditions, over 75% of flies expressing qsmdsRNA.Scer\UAS under the control of Scer\GAL4tim.PE show robust locomotor activity rhythmicity, with an average period ranging from 26.6 to 28.5 hours (depending on the lines used), whereas control animals are largely arrhythmic under these conditions.

76.4% of flies expressing qsmdsRNA.Scer\UAS under the control of Scer\GAL4qsm-NP2664 in a qsmNP2664/+ background show robust locomotor activity rhythmicity under dim constant light conditions.

50% of flies expressing qsmdsRNA.Scer\UAS under the control of Scer\GAL4qsm-NP6258 in a qsmNP6258/+ background show robust locomotor activity rhythmicity under dim constant light conditions.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
qsmRNAi.UAS
qsmdsRNA.Scer\UAS
qsmdsRNA.UAS
Name Synonyms
Secondary FlyBase IDs
    References (4)