FB2024_03 , released June 25, 2024
Allele: Dmel\Gαqpept.UAS
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General Information
Symbol
Dmel\Gαqpept.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0264674
Feature type
allele
Associated gene
Dmel\Gαq
Associated Insertion(s)
Carried in Construct
P{UAS-Gαq.pept}
Key Links
Transgenic product class
dominant_negative_variant
(Yao and Carlson, 2010)
Mutagen
Nature of the Allele
Transgenic product class
dominant_negative_variant
(Yao and Carlson, 2010)
Mutagen
in vitro construct
(Yao and Carlson, 2010)
Progenitor genotype
Carried in construct
P{UAS-Gαq.pept}
Cytology
Description

UAS regulatory sequences are fused upstream of a start codon, a glycine and the 11 C-terminal amino acids of Gαq. The encoded product should act as a competitive peptide and knock down Gαq activity.

(Yao and Carlson, 2010)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Gαq
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The odour responses of the ab1A, ab2A and ab3A olfactory receptor neurons are unaffected in animals expressing Gα49Bpept.Scer\UAS under the control of Scer\GAL4Orco.T:Hsim\VP16.

      The response of the ab1C neuron to CO[[2]] is reduced over a wide range of concentrations in animals expressing Gα49Bpept.Scer\UAS under the control of Scer\GAL4Gr21a.9.323.

      (Yao and Carlson, 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Gα49Bpept.Scer\UAS
      Gαqpept.Scer\UAS
      Gαqpept.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (1)