FB2024_03 , released June 25, 2024
Allele: Dmel\HUAS.cUa
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General Information
Symbol
Dmel\HUAS.cUa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Unknown
FlyBase ID
FBal0264897
Feature type
allele
Associated gene
Dmel\H
Associated Insertion(s)
Carried in Construct
P{UAS-H.U}
Also Known As
UAS-H, UAS-Hairless
Key Links
Transgenic product class
wild_type
(Bardin et al., 2010)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Bardin et al., 2010)
Mutagen
in vitro construct
(Bardin et al., 2010)
Progenitor genotype
Carried in construct
P{UAS-H.U}
Cytology
Description

UAS regulatory sequences drive expression of H.

(Bardin et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
H
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Under control conditions, the adulthood-only expression of HScer\UAS.cUa under the control of Scer\GAL4esg-NP7397 (and Gal80[ts], for the temporal regulation of expression) leads to a significant increase in the adult posterior midgut mitotic index in females only, as compared to controls.

      (Hudry et al., 2016)

      Scer\GAL4Dl-NP0677-mediated expression increases the number of intestinal stem cells in the adult midgut.

      (Foronda et al., 2014)

      Expression of HScer\UAS.cUa under the control of Scer\GAL4tub.PU in intestinal stem cell (ISC) clones results in a large increase in clone size compared to wild-type clones and results in additional, small ISC-like cells.

      (Bardin et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      HScer\UAS.cUa
      HUAS.cUa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Unknown
      Secondary FlyBase IDs
        References (8)