FB2024_03 , released June 25, 2024
Allele: Dmel\Inx2NIG.4590R
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General Information
Symbol
Dmel\Inx2NIG.4590R
Species
D. melanogaster
Name
FlyBase ID
FBal0265866
Feature type
allele
Associated gene
Dmel\Inx2
Associated Insertion(s)
Carried in Construct
P{NIG.4590R}
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Mukai et al., 2011)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Mukai et al., 2011)
Mutagen
in vitro construct
(Mukai et al., 2011)
Progenitor genotype
Carried in construct
P{NIG.4590R}
Cytology
Description

UASt regulatory sequences drive expression of an Inx2 RNAi construct.

(Mukai et al., 2011)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
dsRNA-4590R
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of Inx2NIG.4590R under the control of Scer\GAL4tj.PU (along with expression of UAS-Dcr2 to increase RNAi efficiency) results in semi-sterility.

      (Smendziuk et al., 2015)

      Expression of Inx2NIG.4590R under the control of Scer\GAL4C587 results in ovaries arresting in early oogenesis. The germaria in these females appear to contain only early germ cells with single spectrosomes. The number of germ cells is reduced.

      (Mukai et al., 2011)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Inx2NIG.4590R
      inx24590R-2
      (Smendziuk et al., 2015)
      inx2NIG.4590R
      Name Synonyms
      Secondary FlyBase IDs
        References (4)