Recombination between the two progenitor insertions has resulted in the deletion of the intervening sequence between them. The deletion is 460bp and includes the potential start codon.
Recombination between the two progenitor insertions has resulted in the deletion of the intervening sequence between them. The deletion is 460bp and includes the potential start codon.
Mutants show female sterility, decreased egg laying and abnormal egg appendages.
Approximately 92% of ovarioles contain more than one pro-oocyte nucleus in stage one mutant egg chambers. Mutant egg chambers show loss of the oocyte (by marker expression analysis) after stage 2 of oogenesis in at least 48% of 2-day old females, and the penetrance of this phenotype increases with age.
Germline stem cells with round fusomes and differentiating cysts with branched fusomes are detected even 15 days after eclosion, indicating that maintenance or differentiation of germline stem cells is not defective in the mutant females.
qinM41-13 is rescued by Scer\GAL4nanos.PU/qinUASp.Tag:MYC
qinM41-13 is partially rescued by qinCT.UASp.Tag:MYC/Scer\GAL4nanos.PU
qinM41-13 is not rescued by qinNT.UASp.Tag:MYC/Scer\GAL4nanos.PU
Expression of qinNT.Scer\UAS.P\T.T:Hsap\MYC under the control of Scer\GAL4nos.PU fails to rescue the sterility of qinM41-13 females.
Expression of qinCT.Scer\UAS.P\T.T:Hsap\MYC under the control of Scer\GAL4nos.PU partially rescues the sterility of qinM41-13 females.
