FB2024_03 , released June 25, 2024
Allele: Dmel\rprGMR.PD
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General Information
Symbol
Dmel\rprGMR.PD
Species
D. melanogaster
Name
FlyBase ID
FBal0268099
Feature type
allele
Associated gene
Dmel\rpr
Associated Insertion(s)
Carried in Construct
PBac{GMR-rpr.PD}
Key Links
Transgenic product class
wild_type
(Domingues and Ryoo, 2012)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Domingues and Ryoo, 2012)
Mutagen
in vitro construct
(Domingues and Ryoo, 2012)
Progenitor genotype
Carried in construct
PBac{GMR-rpr.PD}
Cytology
Description

GMR regulatory sequences drive expression of rpr coding sequences.

(Domingues and Ryoo, 2012)
Allele components
Component
Use(s)
Regulatory region(s)
GMR
Encoded product / tool
rpr
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      rprGMR.PD expression in the developing eye results in partial eye ablation.

      (Domingues and Ryoo, 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      rprGMR.PD has eye phenotype, enhanceable by BruceE81/Bruce[+]

      (Domingues and Ryoo, 2012)

      rprGMR.PD has eye phenotype, enhanceable by Bruce[+]/BruceE23

      (Domingues and Ryoo, 2012)
      Suppressed by
      Statement
      Reference

      rprGMR.PD has eye phenotype, suppressible by BruceUAS.Tag:MYC/Scer\GAL4GMR.PF

      (Domingues and Ryoo, 2012)

      rprGMR.PD has eye phenotype, suppressible | partially by BruceBIR.UAS/Scer\GAL4GMR.PF

      (Domingues and Ryoo, 2012)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      A BruceE81 or BruceE23 heterozygous background dominantly enhances the rprGMR.PD eye ablation phenotype.

      Expression of BruceBIR.Scer\UAS under the control of Scer\GAL4GMR.PF moderately suppresses the partial eye ablation seen in rprGMR.PD eyes.

      Expression of BruceScer\UAS.T:Hsap\MYC under the control of Scer\GAL4GMR.PF completely suppresses the partial eye ablation seen in rprGMR.PD eyes.

      (Domingues and Ryoo, 2012)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      rprGMR.PD
      Name Synonyms
      Secondary FlyBase IDs
        References (1)