Expression of Scer\GAL4^GMR.PS>caz^{dsRNA.1-167.Scer\UAS} in eye imaginal discs induces morphologically aberrant rough eyes. Scanning electron microscope (SEM) images show fusion of ommatidia and loss of mechanosensory bristles.

Knockdown of caz in all tissues, through expression of caz^{dsRNA.1-167.Scer\UAS} under the control of Scer\GAL4^Act5C.PI, results in late pupal lethality. Knockdown of caz in the developing eye, in the region posterior to the morphogenetic furrow, under the control of Scer\GAL4^GMR.PS, induces morphologically aberrant rough eyes. SEM images show fusion of ommatidia and a lack of bristles.

Expression of caz^{dsRNA.1-167.Scer\UAS} under the control of Scer\GAL4^Act5C.PI results in pupal lethality at 28[o]C (all lines analysed), but results in viability at 25[o]C (for most lines analysed).

Flies expressing caz^{dsRNA.1-167.Scer\UAS} under the control of Scer\GAL4^elav.PLu show no significant difference in life span compared to control flies. The flies show reduced ability in a climbing assay compared to controls.

The total length of synaptic branches and the number of boutons at the neuromuscular junction are reduced compared to wild type in larvae expressing caz^{dsRNA.1-167.Scer\UAS} under the control of Scer\GAL4^elav.PLu, while bouton size is normal.