FlyBase Allele Report: Dmel\fabp[GX62810]

General Information

Symbol

Dmel\fabp^GX62810

Species

D. melanogaster

Name

FlyBase ID

FBal0278375

Feature type

allele

Associated gene

Dmel\fabp

Associated Insertion(s)

P{EP}fabp^GX62810

Carried in Construct

Also Known As

GX62810

Key Links

Allele class

Mutagen

Delta2-3 transposase

Nature of the Allele

Allele class

Mutagen

Delta2-3 transposase

(Paik et al., 2012)

Progenitor genotype

Associated Insertion(s)

P{EP}fabp^GX62810

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{EP}

misexpression element

Regulatory region(s)

UAS

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal circadian rhythm | adult stage, with Scer\GAL4^elav-C155

(Jang et al., 2022)

abnormal locomotor behavior | adult stage, with Scer\GAL4^elav-C155

(Jang et al., 2022)

abnormal locomotor behavior | adult stage, with Scer\GAL4^repo

(Jang et al., 2022)

abnormal oxidative stress response, with Scer\GAL4^da.G32

(Lee et al., 2012)

increased cell death | adult stage, with Scer\GAL4^repo

(Jang et al., 2022)

increased cell number | adult stage, with Scer\GAL4^elav-C155

(Jang et al., 2022)

increased cell number | adult stage, with Scer\GAL4^repo

(Jang et al., 2022)

increased size | adult stage, with Scer\GAL4^ptc-559.1

(Jang et al., 2022)

long lived, with Scer\GAL4^da.G32

(Lee et al., 2012)

partially lethal, with Scer\GAL4^elav-C155

(Jang et al., 2022)

partially lethal, with Scer\GAL4^repo

(Jang et al., 2022)

some die during embryonic stage, with Scer\GAL4^elav-C155

(Jang et al., 2022)

some die during embryonic stage, with Scer\GAL4^repo

(Jang et al., 2022)

visible | adult stage, with Scer\GAL4^ptc-559.1

(Jang et al., 2022)

Phenotype Manifest In

adult brain, with Scer\GAL4^repo

(Jang et al., 2022)

adult CNS glial cell | increased number, with Scer\GAL4^elav-C155

(Jang et al., 2022)

adult CNS glial cell | increased number, with Scer\GAL4^repo

(Jang et al., 2022)

wing, with Scer\GAL4^ptc-559.1

(Jang et al., 2022)

Detailed Description

Statement

Reference

Expression of fabp^GX62810 under the control of Scer\GAL4^da.G32 results in an increase in median lifespan compared to controls.

Flies expressing fabp^GX62810 under the control of Scer\GAL4^da.G32 show a smaller increase in lifespan with dietary restriction compared to wild-type controls.

Flies expressing fabp^GX62810 under the control of Scer\GAL4^da.G32 show increased resistance to oxidative stress compared to wild type.

(Lee et al., 2012)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

Part of the GX series of enhancer piracy (EP) lines generated at GenExel Inc. in the Republic of Korea.

(Paik et al., 2012)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

EP^CG6783

(Lee et al., 2012)

dFabp^EP6783

(Jang et al., 2022)

fabp^GX62810

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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