Expression of Inx7dsRNA.Scer\UAS under the control of Scer\GAL4hs.PB results in disruption of the longitudinal, posterior and anterior commissures in the embryonic CNS. Holes are often found in the ventral nerve cord. Outgrowth of axon fibres of the ventral nerve cord does not occur properly, resulting in defects in the peripheral nervous system.
Expression of Inx7dsRNA.Scer\UAS under the control of Scer\GAL4sim.P3.7 results in intrasegmental fusion of the ventral nerve cord and disruption to the longitudinal, posterior and anterior commissures in the CNS.