FlyBase Allele Report: Dmel\AdamTS-B[HMC02914]

General Information

Symbol

Dmel\AdamTS-B^HMC02914

Species

D. melanogaster

Name

FlyBase ID

FBal0292186

Feature type

allele

Associated gene

Dmel\AdamTS-B

Associated Insertion(s)

Carried in Construct

P{TRiP.HMC02914}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

(Ni et al., 2010.12.1)

Progenitor genotype

Carried in construct

P{TRiP.HMC02914}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-HMC02914

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal size | adult stage, with Scer\GAL4^Bx-MS1096

(Pham et al., 2018)

abnormal size | adult stage, with Scer\GAL4^en.PU

(Pham et al., 2018)

abnormal size | adult stage, with Scer\GAL4^nub.PU

(Pham et al., 2018)

partially lethal - majority die, with Scer\GAL4^Act5C.PU

(Pham et al., 2018)

visible | adult stage, with Scer\GAL4^Bx-MS1096

(Pham et al., 2018)

Phenotype Manifest In

posterior crossvein, with Scer\GAL4^Bx-MS1096

(Pham et al., 2018)

posterior crossvein, with Scer\GAL4^en.PU

(Pham et al., 2018)

posterior crossvein, with Scer\GAL4^nub.PU

(Pham et al., 2018)

wing, with Scer\GAL4^Bx-MS1096

(Pham et al., 2018)

wing vein L5, with Scer\GAL4^Bx-MS1096

(Pham et al., 2018)

wing vein L5, with Scer\GAL4^en.PU

(Pham et al., 2018)

wing vein L5, with Scer\GAL4^nub.PU

(Pham et al., 2018)

Detailed Description

Statement

Reference

Expression of AdamTS-B^HMC02914 under the control of Scer\GAL4^Bx-MS1096 leads to a wondering wing vein L5, wings with a significantly larger length/width ratio and either an extra branch on the posterior crossvein (PCV), a delta at the PCV or a wider PCV compared to controls.

Expression of AdamTS-B^HMC02914 under the control of Scer\GAL4^en.PU or Scer\GAL4^nub.PU leads to a wider PCV and a wondering wing vein L5 compared to controls.

(Pham et al., 2018)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions