FB2024_03 , released June 25, 2024
Allele: Dmel\S6kRNAi.UAS.cUa
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General Information
Symbol
Dmel\S6kRNAi.UAS.cUa
Species
D. melanogaster
Name
FlyBase ID
FBal0296354
Feature type
allele
Associated gene
Dmel\S6k
Associated Insertion(s)
Carried in Construct
P{UAS-S6k.RNAi.U}
Key Links
Transgenic product class
RNAi_reagent
(Tixier et al., 2013)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Tixier et al., 2013)
Mutagen
in vitro construct
(Tixier et al., 2013)
Progenitor genotype
Carried in construct
P{UAS-S6k.RNAi.U}
Cytology
Description

UAS regulatory sequences drive expression of a S6k RNAi line.

(Tixier et al., 2013)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
S6k
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      ameliorates  brain cancer
      modeled by bratRNAi.UAS.cUa
      (Mukherjee et al., 2018)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Embryos expressing S6kdsRNA.Scer\UAS.cUa under the control of Scer\GAL4kirre.PU show a significant reduction in the size of the segmental border muscle and the DA1 muscle, and also in the number of nuclei present in these muscles.

      (Tixier et al., 2013)

      Embryos expressing S6kdsRNA.Scer\UAS.cUa under the control of Scer\GAL4kirre.PU have thinner muscles than normal and unfused myoblasts are present.

      (Tixier et al., 2013)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      S6kRNAi.UAS.cUa
      S6kdsRNA.Scer\UAS.cUa
      S6kdsRNA.UAS.cUa
      Name Synonyms
      Secondary FlyBase IDs
        References (5)