FB2024_03 , released June 25, 2024
Allele: Dmel\DuoxRNAi.UAS.cUa
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General Information
Symbol
Dmel\DuoxRNAi.UAS.cUa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Unknown
FlyBase ID
FBal0302859
Feature type
allele
Associated gene
Dmel\Duox
Associated Insertion(s)
Carried in Construct
P{UAS-Duox.RNAi.U}
Key Links
Transgenic product class
RNAi_reagent
(Lee et al., 2015)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Lee et al., 2015)
Mutagen
in vitro construct
(Lee et al., 2015)
Progenitor genotype
Carried in construct
P{UAS-Duox.RNAi.U}
Cytology
Description

UAS regulatory sequences drive expression of an RNAi construct targeting Duox.

(Lee et al., 2015)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Duox
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 1 )
      Disease
      Evidence
      References
      model of  primary bacterial infectious disease
      CEA
      (Lee et al., 2015)
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Adults expressing DuoxdsRNA.UAS.cUa under the control of Scer\GAL4NP0001 exhibit significantly higher mortality to Ecc15 enteric infection, as compared to controls; the same is observed when expression is driven by Scer\GAL4hs.PB and induced by 29[o]C.

      (Lee et al., 2018)

      Host survival is compromised after E. carotovora infection in flies expressing DuoxdsRNA.Scer\UAS.cUa under the control of the enterocyte-specific driver Scer\GAL4Myo31DF-NP0001.

      (Lee et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (6)
      Reported As
      Symbol Synonym
      CydsRNA.Scer\UAS.cUa
      DuoxRNAi.UAS.cUa
      DuoxRNAi
      (Wang et al., 2015)
      DuoxdsRNA.Scer\UAS.cUa
      DuoxdsRNA.UAS.cUa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Unknown
      Secondary FlyBase IDs
        References (4)