UASt regulatory sequences drive expression of a non-phosphorylated form of HDAC1 (carries the S419A and S421A mutations).
abnormal heat stress response | adult stage, with Scer\GAL4tin.CΔ4
long lived, with Scer\GAL4tin.CΔ4
adult heart
Expression of HDAC1ADA.Scer\UAS under the control of Scer\GAL4tin.CΔ4 leads to increased survival and higher heart rate under heat stress, as compared to equally stressed controls.