FB2024_03 , released June 25, 2024
Allele: Dmel\RxUAS.cKa
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General Information
Symbol
Dmel\RxUAS.cKa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Kiewe
FlyBase ID
FBal0325868
Feature type
allele
Associated gene
Dmel\Rx
Associated Insertion(s)
Carried in Construct
P{UAS-Rx.K}
Key Links
Transgenic product class
cDNA
(Kraft et al., 2016)
wild_type
(Kraft et al., 2016)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Kraft et al., 2016)
wild_type
(Kraft et al., 2016)
Mutagen
in vitro construct
(Kraft et al., 2016)
Progenitor genotype
Carried in construct
P{UAS-Rx.K}
Cytology
Description

UASt regulatory sequences drive expression of Rx cDNA.

(Kraft et al., 2016)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Rx
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of RxScer\UAS.cKa under the control of Scer\GAL4insc-Mz1407 or Scer\GAL4elav-C155 results in an increase in the diameter of third instar mushroom body neuroblasts (NBs) and GMCs, but no significant increase in the mitotic index of mushroom body NBs, basolateral dorsal NBs or basolateral posterior NBs; expression of RxScer\UAS.cKa under the control of Scer\GAL4insc-Mz1407 results in an increase in the diameter of basolateral dorsal NBs and GMCs, and basolateral posterior NBs and GMCs, as compared to wild type.

      Expression of RxScer\UAS.cKa under the control of Scer\GAL4wor.PU or Scer\GAL4insc-Mz1407 does not affect the longevity of mushroom body NBs, as compared to controls.

      (Kraft et al., 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      RxScer\UAS.cKa
      RxUAS.cKa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Kiewe
      Secondary FlyBase IDs
        References (2)