FB2024_03 , released June 25, 2024
Allele: Dmel\omd126
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General Information
Symbol
Dmel\omd126
Species
D. melanogaster
Name
FlyBase ID
FBal0348394
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Nature of the Allele
Allele class
Progenitor genotype
Cytology
Description

G to A mutation at the splice donor site of the first intron of omd.

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Nucleotide change:

G13683026A

Comment:

Nucleotide substitution: GT changed to AT in the splice donor.

Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

omd348 type I neuroblast clones in the larval brain contain the same single neuroblast per clone as controls, but also contain small ectopic Dpn-positive, Ase-negative daughter cells of unknown cell identity and origin at the vicinity of ganglion mother cells.

omd126 type II neuroblast clones in the larval brain contain many supernumerary neuroblast-like cells (including Dpn-positive, Ase-negative, Worniu-positive neuroblast-like cells), and significantly fewer neurons and intermediate neural progenitor-like cells (both immature Dpn-negative, PntP1-positive or Dpn-negative, Erm-positive INPs or mature Dpn-positive, Ase-positive INPs), as compared to controls.

External Data
Interactions
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Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
omd126
Name Synonyms
Secondary FlyBase IDs
    References (1)