FB2024_03 , released June 25, 2024
Allele: Dmel\HUAS.cWa
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General Information
Symbol
Dmel\HUAS.cWa
Species
D. melanogaster
Name
UAS construct a of Wolf
FlyBase ID
FBal0353217
Feature type
allele
Associated gene
Dmel\H
Associated Insertion(s)
Carried in Construct
M{UAS-H.W}
Key Links
Transgenic product class
cDNA
(Wolf et al., 2019)
wild_type
(Wolf et al., 2019)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Wolf et al., 2019)
wild_type
(Wolf et al., 2019)
Mutagen
in vitro construct
(Wolf et al., 2019)
Progenitor genotype
Carried in construct
M{UAS-H.W}
Cytology
Description

UASt regulatory sequences drive expression of wild-type H cDNA.

(Wolf et al., 2019)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
H
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The expression of HUAS.cWa under the control of Scer\GAL4bi-omb-Gal4 induces drastic wing notches and ectopic wing veins material.

      (Wolf et al., 2019)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhanced by
      Enhancer of
      Other
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      HUAS.cWa, Scer\GAL4bi-omb-Gal4 has wing phenotype, enhanceable by Su(H)UAS.cUa, Scer\GAL4bi-omb-Gal4

      (Wolf et al., 2019)
      Enhancer of
      Statement
      Reference

      HUAS.cWa, Scer\GAL4bi-omb-Gal4 is an enhancer of wing phenotype of Scer\GAL4bi-omb-Gal4, Su(H)UAS.cUa

      (Wolf et al., 2019)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The co-expression of Su(H)UAS.cUa and HUAS.cWa under the control of Scer\GAL4bi-omb-Gal4 leads to rudimentary wings; these are more severe defects than those induced by either single expression - i.e. wing notches for HUAS.cWa and crumbled wings for Su(H)UAS.cUa.

      (Wolf et al., 2019)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      HUAS.cWa
      Name Synonyms
      UAS construct a of Wolf
      Secondary FlyBase IDs
        References (1)