Insertion of a PBac{SAstopDsRed} gene trap element insertion into the seventh coding exon of bchs at amino acid residue 1229 preceeding the BEACH domain.
vesicle | larval stage (with Df(2L)cl7)
bchsLL03462/Df(2L)cl7 transheterozygous larvae exhibit a significant decrease in the number of RP2 motor neurons, compared to controls.
Cultured bchsLL03462/Df(2L)cl7 larval neurons exhibit significantly more Atg5-positive vesicles than controls, whereas the number of Atg8-positive autophagosomes is not significantly affected.
Df(2L)cl7/bchsLL03462 is rescued by Scer\GAL4eve.PU/bchsUAS.1.GFP