FB2024_03 , released June 25, 2024
Allele: Dmel\Ciao1Δ60
Open Close
General Information
Symbol
Dmel\Ciao1Δ60
Species
D. melanogaster
Name
FlyBase ID
FBal0361052
Feature type
allele
Associated gene
Dmel\Ciao1
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

hypomorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - molecular evidence

(Jung et al., 2020)
Mutagen
P-element activity
(Jung et al., 2020)
Progenitor genotype
P{EPgy2}Ciao1EY11076
(Jung et al., 2020)
Cytology
Description

926bp deletion within Ciao1. Generated by imprecise excision of P{EPgy2}Ciao1EY11076; deletion extends downstream from the original site of the insertion in the 5'UTR.

(Jung et al., 2020)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
2R:14,854,070..14,854,995 [-]
Comment:

Reported as a 926bp deletion resulting from the imprecise excision of P{EPgy2}Ciao1EY11076 that extends from the original insertion site into Ciao1.

(Jung et al., 2020)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Ciao1Δ60 clones in the eye discs are small and often lost in third instar larvae.

      Eyes specific Ciao1Δ60 clones generated using EGUF/hid method with Scer\GAL4ey.PU lead to a reduction in the eye size.

      (Jung et al., 2020)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      Ciao1Δ60/Ciao1[+] is a suppressor of visible | adult stage phenotype of Scer\GAL4GMR.PU, crbintra.UAS

      (Jung et al., 2020)

      Ciao1Δ60/Ciao1[+] is a suppressor of decreased size | adult stage phenotype of Scer\GAL4GMR.PU, crbintra.UAS

      (Jung et al., 2020)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Ciao1Δ60/Ciao1[+] is a suppressor of eye phenotype of Scer\GAL4GMR.PU, crbintra.UAS

      (Jung et al., 2020)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      Ciao1Δ60 is rescued by Scer\GAL4Act5C.PU/Ciao1UAS.cJa

      (Jung et al., 2020)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Ciao1Δ60
      (Jung et al., 2020)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)