lethal | maternal effect (with mv1)
centrosome | embryonic stage 4 | maternal effect (with mv1)
chromosome | embryonic stage | maternal effect (with Df(3L)R-G7)
chromosome | embryonic stage | maternal effect (with mv1)
lipid droplet | embryonic stage (with mv3)
nucleus | embryonic stage 4 | maternal effect (with mv1)
Embryos from mvros/Df(3L)R-G7 mothers show enlarged yolk granules. A small fraction shows aberrant mitotic spindles of different sizes associated with varying amounts of DNA, abnormal chromosome segregation and multiple centrosomes often in chains; the majority reaches the syncytial blastoderm stage but exhibit localized MTOC inactivation and loss of contact between nuclei and centrosomes at the cortex, leading nuclei to sink into the interior of the embryo (nuclear fallout); in live imaging, cortical migration of nuclei is followed by an abrupt flow of cytoplasm from within the embryo toward the surface, displacing the cortical nuclei toward the embryo's poles and leading to the surfacing of yolk nuclei, which normally get left behind in the embryo's interior.
Stage 4 embryos from mvros/mv1 mothers show multiple centrosomes often in chains
Df(3L)R-G7/mvros has abnormal mitotic cell cycle | embryonic stage | maternal effect phenotype, enhanceable by Df(3R)Exel6142/+
Df(3L)R-G7/mvros has abnormal mitotic cell cycle | embryonic stage | maternal effect phenotype, enhanceable by mspsMJ208/msps[+]
Df(3L)R-G7/mvros has increased size | maternal effect | embryonic stage phenotype, suppressible | partially by Rab5S43N.UAS/Scer\GAL4VP16.mat.αTub67C
Df(3L)R-G7/mvros has increased size | maternal effect | embryonic stage phenotype, non-suppressible by Rab7Q67L.UASp.YFP/Scer\GAL4VP16.mat.αTub67C
Df(3L)R-G7/mvros has mitotic spindle | embryonic stage | maternal effect phenotype, enhanceable by Df(3R)Exel6142/+
Df(3L)R-G7/mvros has FlyBase_internalproperty type:chromosome:chromosome | embryonic stage | maternal effect phenotype, enhanceable by Df(3R)Exel6142/+
Df(3L)R-G7/mvros has centrosome | embryonic stage 4 | maternal effect phenotype, enhanceable by Df(3R)Exel6142/+
Df(3L)R-G7/mvros has FlyBase_internalproperty type:chromosome:chromosome | embryonic stage | maternal effect phenotype, enhanceable by mspsMJ208/msps[+]
Df(3L)R-G7/mvros has centrosome | embryonic stage 4 | maternal effect phenotype, enhanceable by mspsMJ208/msps[+]
Df(3L)R-G7/mvros has mitotic spindle | embryonic stage | maternal effect phenotype, enhanceable by mspsMJ208/msps[+]
Df(3L)R-G7/mvros has yolk granule | maternal effect | embryonic stage phenotype, suppressible | partially by Rab5S43N.UAS/Scer\GAL4VP16.mat.αTub67C
Df(3L)R-G7/mvros has yolk granule | maternal effect | embryonic stage phenotype, non-suppressible by Rab7Q67L.UASp.YFP/Scer\GAL4VP16.mat.αTub67C
Df(3L)R-G7/mvros is rescued by mvTag:CALI(TC),Tag:FLAG/Scer\GAL4VP16.mat.αTub67C
Df(3L)R-G7/mvros is rescued by mvmCherry