CP2, LCP-2
Please see the JBrowse view of Dmel\Lcp2 for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Low-frequency RNA-Seq exon junction(s) not annotated.
Apparent introns not annotated: probable artifacts due to repetitive sequence.
Gene model reviewed during 5.46
Gene model reviewed during 5.56
0.5-0.6 (northern blot)
126 (aa)
17.5 (kD observed)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Lcp2 using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
Lcp2 is expressed in the integument of late third instar larvae.
JBrowse - Visual display of RNA-Seq signals
View Dmel\Lcp2 in JBrowse2-58
2-57.6
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Cis-regulatory regions required for the normal expression of Lcp2 have been identified using deletion constructs.
One of a series of genes encoding electrophoretically separable proteins extractable from the cuticles of third instar larvae, but not other stages. Four immunologically related proteins are encoded by a cluster of genes on 2R and another cluster of three unrelated to the preceding four, but related to each other, located on 3L. Lcp2 encodes larval cuticle protein CP2 (alternatively L3CP2); molecular weight 17.5kD. Has a 15-residue signal peptide.