Int6, l(3)10547, eIF3-S6, Int6 homologue
Please see the JBrowse view of Dmel\eIF3e for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.46
1.5 (northern blot)
There is only one protein coding transcript and one polypeptide associated with this gene
435 (aa); 48 (kD observed)
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex. The eIF-3 complex interacts with pix. Interacts with mxt (PubMed:23716590).
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\eIF3e using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
Comment: maternally deposited
Int6 transcripts are detected at all developmental stages tested. Levels are particularly high in early embryos.
Int6 protein is detected at all developmental stages tested. Levels are particularly high in early embryos.
JBrowse - Visual display of RNA-Seq signals
View Dmel\eIF3e in JBrowse3-44
3-39.4
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
polyclonal
S2 cells treated with dsRNA generated against this gene show reduced phagocytosis of Candida albicans compared to untreated cells.
Source for merge of: Int6 l(3)10547
Source for identity of: eIF3e Int6