FB2024_04 , released June 25, 2024
Gene: Dmel\Mipp1
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General Information
Symbol
Dmel\Mipp1
Species
D. melanogaster
Name
Multiple inositol polyphosphate phosphatase 1
Annotation Symbol
CG4123
Feature Type
protein_coding_gene
FlyBase ID
FBgn0026061
Gene Model Status
Current
Stock Availability
12 publicly available
Enzyme Name (EC)
acid phosphatase (3.1.3.2)
2,3-bisphosphoglycerate 3-phosphatase (3.1.3.80)
Gene Summary
Multiple inositol polyphosphate phosphatase 1 (Mipp1) encodes a highly conserved extracellular enzyme that removes phosphates from inositol polyphosphates (IP6, IP5 and IP4) to form IP3. The Mipp1 product functions extracellularly to promote filopodia formation. Its enzymatic activity and localization are both key during tracheal cell migration. [Date last reviewed: 2018-10-18] (FlyBase Gene Snapshot)
All Summaries
Key Links
Genomic Location
Cytogenetic map
73A7-73A9
Sequence location
Recombination map
3-44
RefSeq locus
NT_037436 REGION:16563448..16573334
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
Gene Ontology (GO) Annotations (11 terms)
Molecular Function (4 terms)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
enables inositol phosphate phosphatase activity
inferred from direct assay
(Cheng and Andrew, 2015)
Terms Based on Predictions or Assertions (4 terms)
CV Term
Evidence
References
enables acid phosphatase activity
inferred from biological aspect of ancestor with PANTHER:PTN001076439
(GO Reference Genome Project, 2011-)
enables bisphosphoglycerate 3-phosphatase activity
inferred from sequence or structural similarity with UniProtKB:Q9UNW1
(Gene Ontology Curators, 2002-)
enables inositol phosphate phosphatase activity
inferred from biological aspect of ancestor with PANTHER:PTN000469221
(GO Reference Genome Project, 2011-)
enables phosphatase activity
inferred from electronic annotation with InterPro:IPR016274
(InterPro Project Members, 2004-)
Biological Process (3 terms)
Terms Based on Experimental Evidence (2 terms)
CV Term
Evidence
References
involved_in open tracheal system development
inferred from mutant phenotype
(Cheng and Andrew, 2015)
involved_in positive regulation of filopodium assembly
inferred from mutant phenotype
(Cheng and Andrew, 2015)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
involved_in dephosphorylation
inferred from sequence or structural similarity with UniProtKB:Q9UNW1
(Gene Ontology Curators, 2002-)
Cellular Component (4 terms)
Terms Based on Experimental Evidence (3 terms)
CV Term
Evidence
References
located_in external side of plasma membrane
inferred from direct assay
(Cheng and Andrew, 2015)
located_in filopodium
inferred from direct assay
(Cheng and Andrew, 2015)
located_in plasma membrane
inferred from high throughput direct assay
(Tan et al., 2009)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
located_in extracellular exosome
inferred from sequence or structural similarity with UniProtKB:Q9UNW1
(Gene Ontology Curators, 2002-)
Gene Group (FlyBase)
Protein Family (UniProt)
Belongs to the histidine acid phosphatase family. MINPP1 subfamily. (Q9VV72)
Protein Signatures (InterPro)
Catalytic Activity (EC/Rhea)
acid phosphatase activity
a phosphate monoester + H2O = an alcohol + phosphate (3.1.3.2)
bisphosphoglycerate 3-phosphatase activity
(2R)-2,3-bisphosphoglycerate + H2O = (2R)-2-phosphoglycerate + phosphate (3.1.3.80)
RHEA 27381:
Summaries
Gene Snapshot
Multiple inositol polyphosphate phosphatase 1 (Mipp1) encodes a highly conserved extracellular enzyme that removes phosphates from inositol polyphosphates (IP6, IP5 and IP4) to form IP3. The Mipp1 product functions extracellularly to promote filopodia formation. Its enzymatic activity and localization are both key during tracheal cell migration. [Date last reviewed: 2018-10-18]
Gene Group (FlyBase)
PHOSPHATIDYLINOSITOL PHOSPHATE AND INOSITOL PHOSPHATE PHOSPHATASES -
Phosphoinositide phosphate (PtdInsP) phosphatases and Inositol phosphate (InsP) phosphatases are enzymes that catalyze the hydrolysis of phosphate groups from inositol. Many of these phosphatases can act on both PtdInsP and InsP substrates. (Adapted from PMID:23681533).
ACID PHOSPHATASES -
Acid phosphatases catalyse the hydrolysis of orthophosphate monoesters under acidic conditions. Their precise functional roles are largely unknown. (Adapted from PMID:11950951.)
Protein Function (UniProtKB)
Probable multiple inositol polyphosphate phosphatase that hydrolyzes 1D-myo-inositol 1,3,4,5,6-pentakisphosphate (InsP5[2OH]) and 1D-myo-inositol hexakisphosphate (InsP6) to a range of less phosphorylated inositol phosphates. This regulates the availability of these various small molecule second messengers and metal chelators which control many aspects of cell physiology (PubMed:26628373). May have a dual substrate specificity, and function as a 2,3-bisphosphoglycerate 3-phosphatase hydrolyzing 2,3-bisphosphoglycerate to 2-phosphoglycerate. 2,3-bisphosphoglycerate (BPG) is formed as part of the Rapoport-Luebering glycolytic bypass (By similarity). Has a role in embryonic tracheal development where it localizes to the leading edge of actively migrating branches (PubMed:26628373). In these leading cells, enhances formation and/or maintenance of filopodia which may drive branch migration and elongation by cell-cell intercalation (PubMed:26628373). The function in tracheal morphogenesis is dependent on its inositol polyphosphate phosphatase activity (PubMed:26628373).
(UniProt, Q9VV72)
Gene Model and Products
Number of Transcripts
3
Number of Unique Polypeptides
1

Please see the JBrowse view of Dmel\Mipp1 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Structure
Protein 3D structure   (Predicted by AlphaFold)   (AlphaFold entry Q9VV72)

If you don't see a structure in the viewer, refresh your browser.
Model Confidence:
  • Very high (pLDDT > 90)
  • Confident (90 > pLDDT > 70)
  • Low (70 > pLDDT > 50)
  • Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures
Crossreferences
Comments on Gene Model

Gene model reviewed during 5.55

Annotated transcripts do not represent all supported alternative splices within 5' UTR.

Gene model reviewed during 5.45

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene model reviewed during 5.56

Sequence Ontology: Class of Gene
nuclear_gene
protein_coding_gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
Mipp1-RA
FBtr0075399
NM_079385
1828
467
Mipp1-RB
FBtr0075398
NM_168672
1769
467
Mipp1-RC
FBtr0345813
NM_001300153
2009
467
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
UniProt
RefSeq ID
GenBank
Mipp1-PA
FBpp0075157
53.6
467
6.72
Q9VV72
NP_524109
AAF49450
Mipp1-PB
FBpp0075156
53.6
467
6.72
Q9VV72
NP_730177
AAN11754
Mipp1-PC
FBpp0311799
53.6
467
6.72
Q9VV72
NP_001287082
AHN58107
Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

467 aa isoforms: Mipp1-PA, Mipp1-PB, Mipp1-PC
Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Post Translational Modification

N-glycosylated.

(UniProt, Q9VV72)
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Mipp1 using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-0.65

Transcript Expression
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 4 -- 6
dorsal ectoderm anlage

Comment: anlage in statu nascendi

(Fisher et al., 2012)
ventral ectoderm anlage

Comment: anlage in statu nascendi

(Fisher et al., 2012)
embryonic stage 7 -- 8
dorsal ectoderm
(Fisher et al., 2012)
hindgut anlage
(Fisher et al., 2012)
ventral ectoderm
(Fisher et al., 2012)
embryonic stage 9 -- 10
dorsal ectoderm
(Fisher et al., 2012)
inclusive hindgut primordium
(Fisher et al., 2012)
embryonic stage 10 -- 15
presumptive embryonic/larval tracheal system
(Cheng and Andrew, 2015)
embryonic stage 11
embryonic/larval tracheal section
(Chung et al., 2011)
embryonic stage 11 -- 12
dorsal epidermis primordium
(Fisher et al., 2012)
tracheal dorsal trunk primordium

Comment: reported as dorsal trunk specific anlage

(Fisher et al., 2012)
hindgut proper primordium
(Fisher et al., 2012)
secondary branch/tracheole primordium

Comment: reported as tracheole specific anlage

(Fisher et al., 2012)
tracheal primordium
(Fisher et al., 2012)
embryonic stage 13 -- 15
embryonic/larval dorsal tracheal branch
(Cheng and Andrew, 2015)
embryonic/larval visceral tracheal branch
(Cheng and Andrew, 2015)
embryonic/larval ganglionic tracheal branch
(Cheng and Andrew, 2015)
embryonic/larval tracheal lateral trunk
(Cheng and Andrew, 2015)
embryonic stage 13 -- 16
circular visceral muscle fiber
(Fisher et al., 2012)
embryonic foregut
(Fisher et al., 2012)
embryonic hindgut
(Fisher et al., 2012)
embryonic stomatogastric nervous system
(Fisher et al., 2012)
embryonic tracheole
(Fisher et al., 2012)
embryonic/larval pericardial cell
(Fisher et al., 2012)
embryonic/larval visceral muscle cell
(Fisher et al., 2012)
embryonic stage 14 -- 16
embryonic/larval foregut
(Cheng and Andrew, 2015)
embryonic/larval hindgut
(Cheng and Andrew, 2015)
embryonic cardioblast
(Cheng and Andrew, 2015)
Additional Descriptive Data

Mipp1 transcripts are expressed in all tracheal cells from embryonic stage 10-13. In stages 13-15, it is diminished in the dorsal trunk but remains in the dorsal branch, visceral branch, ganglionic branch, and lateral trunk. During stages 10-12, transcripts are located in small puncta throughout the cytoplasm but in stages 13-15, they accumulate in large foci localized to particular regions in each cell type. It appears that the Mipp1 transcripts are A is maintained in migrating branches with enrichment at regions where extensive filopodia form.

(Cheng and Andrew, 2015)
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
immunolocalization
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 10 -- 12
presumptive embryonic/larval tracheal system
(Cheng and Andrew, 2015)
embryonic stage 13 -- 15
embryonic/larval dorsal tracheal branch
(Cheng and Andrew, 2015)
embryonic/larval visceral tracheal branch
(Cheng and Andrew, 2015)
embryonic/larval ganglionic tracheal branch
(Cheng and Andrew, 2015)
embryonic/larval tracheal lateral trunk
(Cheng and Andrew, 2015)
embryonic stage 14 -- 16
embryonic cardioblast
(Cheng and Andrew, 2015)
embryonic stage 16
embryonic/larval foregut
(Cheng and Andrew, 2015)
embryonic/larval hindgut
(Cheng and Andrew, 2015)
mass spectroscopy
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
adult head
(Aradska et al., 2015)
day 5 of adulthood & male -- day 7 of adulthood & male
spermatozoon
(Dorus et al., 2006)
day 7 of adulthood -- day 49 of adulthood
adult heart
(Cammarato et al., 2011)
Additional Descriptive Data

Mipp1 protein expression parallels Mipp1 transcript expression in embryonic tracheal cells. It localizes to the membrane to structures that appear to be filopodea.

(Cheng and Andrew, 2015)
Marker for
 
Subcellular Localization
CV Term
Evidence
References
located_in external side of plasma membrane
inferred from direct assay
(Cheng and Andrew, 2015)
located_in filopodium
inferred from direct assay
(Cheng and Andrew, 2015)
located_in plasma membrane
inferred from high throughput direct assay
(Tan et al., 2009)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\Mipp1 in JBrowse
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyExpress - Embryonic expression images (BDGP data)
  • Stages(s) 4-6
  • Stages(s) 7-8
  • Stages(s) 9-10
  • Stages(s) 11-12
  • Stages(s) 13-16
FlyBase Wiki
Image Based Resources
Alleles, Insertions, Transgenic Constructs, and Aberrations
Classical and Insertion Alleles ( 6 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 8 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of Mipp1
Transgenic constructs containing regulatory region of Mipp1
Aberrations (Deficiencies and Duplications) ( 0 )
Inferred from experimentation ( 0 )
Inferred from location ( 0 )
Variants
Variant Molecular Consequences
Alleles Representing Disease-Implicated Variants
Phenotypes
Orthologs
Downloads
Download All DIOPT Orthologs
Human Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Homo sapiens (Human) (2)
Hsap\MINPP1
12 of 14
Yes
No
Hsap\ACP6
1 of 14
No
No
Model Organism Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Rattus norvegicus (Norway rat) (4)
Rnor\Minpp1
11 of 14
Yes
No
Rnor\RGD1564801
9 of 14
No
No
Rnor\Acp2
1 of 14
No
No
Rnor\Acp6
1 of 14
No
No
Mus musculus (laboratory mouse) (3)
Mmus\Minpp1
10 of 14
Yes
No
Mmus\Acp2
1 of 14
No
No
Mmus\Acp6
1 of 14
No
No
Xenopus tropicalis (Western clawed frog) (4)
Xtro\minpp1
8 of 13
Yes
No
Xtro\acp6
1 of 13
No
No
Xtro\LOC100493041
1 of 13
No
No
Xtro\tgfb1
1 of 13
No
No
Danio rerio (Zebrafish) (3)
Drer\minpp1a
12 of 14
Yes
No
Drer\minpp1b
11 of 14
No
No
Drer\acp6
1 of 14
No
No
Caenorhabditis elegans (Nematode, roundworm) (1)
Cele\pho-5
1 of 14
Yes
No
Anopheles gambiae (African malaria mosquito) (2)
Agam\AgaP_AGAP006962
12 of 12
Yes
Yes
Agam\AgaP_AGAP003555
6 of 12
No
No
Arabidopsis thaliana (thale-cress) (1)
Atha\AT1G09870
11 of 13
Yes
No
Saccharomyces cerevisiae (Brewer's yeast) (5)
Scer\DIA3
6 of 13
Yes
Yes
Scer\PHO3
6 of 13
Yes
Yes
Scer\PHO5
6 of 13
Yes
Yes
Scer\PHO11
6 of 13
Yes
Yes
Scer\PHO12
6 of 13
Yes
Yes
Schizosaccharomyces pombe (Fission yeast) (4)
Spom\pho1
8 of 12
Yes
Yes
Spom\pho4
8 of 12
Yes
Yes
Spom\SPBC21H7.03c
8 of 12
Yes
Yes
Spom\SPBC4.06
1 of 12
No
No
Escherichia coli (enterobacterium) (0)
Other Organism Orthologs (via OrthoDB)
Data provided directly from OrthoDB:Mipp1. Refer to their site for version information.
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v9.1)
Gene Symbol
Score
Source
Compara
Domainoid
eggNOG
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Drosophila melanogaster (Fruit fly) (2)
Mipp2
12 of 13
CG9449
1 of 13
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 2 )
    Modifiers Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Interaction
    References
    Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    MINPP1; multiple inositol-polyphosphate phosphatase 1
    12 of 14
    605391
    Functional Complementation Data
    Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
    Interactions
    Summary of Physical Interactions
    esyN Network Diagram
    Other Interaction Browsers
    Summary of Genetic Interactions
    esyN Network Diagram
    Other Interaction Browsers
    Starting gene(s)
    Interaction type
    Interacting gene(s)
    Reference
    Starting gene(s)
    Interaction type
    Interacting gene(s)
    Reference
    External Data
    Linkouts
    DroID - A comprehensive database of gene and protein interactions.
    Pathways
    Signaling Pathways (FlyBase)
    Metabolic Pathways
    FlyCyc Pathways - Pathways from a BioCyc PGDB for Dmel
    KEGG Metabolic Pathways - A collection of manually drawn metabolic pathway maps representing knowledge of molecular interaction, reaction and relation networks.
    External Data
    Linkouts
    KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.
    Genomic Location and Detailed Mapping Data
    Chromosome (arm)
    3L
    Recombination map
    3-44
    Cytogenetic map
    73A7-73A9
    Sequence location
    FlyBase Computed Cytological Location
    Cytogenetic map
    Evidence for location
    73A7-73A9
    Limits computationally determined from genome sequence between P{lacW}l(3)j10E8j10E8&P{PZ}l(3)1053210532 and P{PZ}Baldspot02281
    Experimentally Determined Cytological Location
    Cytogenetic map
    Notes
    References
    Experimentally Determined Recombination Data
    Location

    3-44

    (FlyBase, 2016)

    3-39.2

    (Comeron et al., 2012)
    Left of (cM)
    Right of (cM)
    Notes
    Stocks and Reagents
    Stocks (12)
    Genomic Clones (16)
     

    Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

    cDNA Clones (144)
     

    Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

    cDNA clones, fully sequenced
    BDGP DGC clones
    Other clones
      Drosophila Genomics Resource Center cDNA clones

      For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

      cDNA Clones, End Sequenced (ESTs)
      BDGP DGC clones
      Other clones
      RNAi and Array Information
      Linkouts
      DRSC - Results frm RNAi screens
      Antibody Information
      Laboratory Generated Antibodies
       

      polyclonal

      (Cheng and Andrew, 2015)
      Commercially Available Antibodies
       
      Cell Line Information
      Publicly Available Cell Lines
       
        Other Stable Cell Lines
         
          Other Comments
          Relationship to Other Genes
          Source for database merge of
          Additional comments
          Nomenclature History
          Source for database identify of
          Nomenclature comments
          Etymology
          Synonyms and Secondary IDs (5)
          Datasets (0)
          Study focus (0)
          Experimental Role
          Project
          Project Type
          Title
          Study result (0)
          Result
          Result Type
          Title
          External Crossreferences and Linkouts ( 55 )
          Sequence Crossreferences
          NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
          GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
          GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
          RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
          UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.
          UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information
          Other crossreferences
          AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.
          BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
          DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
          EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
          FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
          FlyMine - An integrated database for Drosophila genomics
          InterPro - A database of protein families, domains and functional sites
          KEGG Genes - Molecular building blocks of life in the genomic space.
          MARRVEL_MODEL - MARRVEL (model organism gene)
          Linkouts
          Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
          DroID - A comprehensive database of gene and protein interactions.
          DRSC - Results frm RNAi screens
          Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
          FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
          FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
          FlyCyc Pathways - Pathways from a BioCyc PGDB for Dmel
          Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
          Flygut - An atlas of the Drosophila adult midgut
          FlyMet - A comprehensive tissue-specific metabolomics resource for Drosophila.
          iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
          KEGG Metabolic Pathways - A collection of manually drawn metabolic pathway maps representing knowledge of molecular interaction, reaction and relation networks.
          KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.
          References (55)