Aats-met, Methionyl-tRNA synthetase
Please see the JBrowse view of Dmel\MetRS-m for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.48
Gene model reviewed during 6.02
The group(s) of polypeptides indicated below share identical sequence to each other.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\MetRS-m using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
Comment: maternally deposited
JBrowse - Visual display of RNA-Seq signals
View Dmel\MetRS-m in JBrowse3-55
3-52.9
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Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Aats-met mutants exhibit lipid droplet accumulation in glia, but this does not lead to premature neurodegeneration.
Source for merge of: Aats-met CG31322
Source for merge of: CG8684 CG9612
Annotations CG8684, CG9612 merged as CG31322 in release 3 of the genome annotation.
Source for merge of CG8684 CG9612 was a shared cDNA ( date:010720 ).
Source for identity of: Aats-met-m Aats-met
Source for identity of: MetRS-m Aats-met-m
Through to FB2015_03, CG31322 was named as 'Aats-met'/'Methionyl-tRNA synthetase', which suggested it encoded the cytoplasmic form of MetRS. However, FBrf0228896 states that CG15100 encodes the cytoplasmic MetRS gene and refers to it as 'MetRS'. Orthology data indicate that CG31322 actually encodes the mitochondrial form of MetRS. Thus, to reduce confusion and improve accuracy, the symbol and fullname of CG31322 have been amended to indicate it's mitochondrial function.