DNA-ligI, DNA ligase I
Please see the JBrowse view of Dmel\DNAlig1 for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.52
There is only one protein coding transcript and one polypeptide associated with this gene
The substrate specificity and mechanism of action of DNAlig1 protein are described. The joining reactions is shown to be reversible.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\DNAlig1 using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
DNAlig1 protein is found in the cytoplasmic fraction of embryonic extracts.
JBrowse - Visual display of RNA-Seq signals
View Dmel\DNAlig1 in JBrowse2-105
2-109.6
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
DNA-ligI protein has been purified, the enzyme physically characterised in 6-12 hour embryos and enzyme activity during development studied.
Source for merge of: DNA-ligI CG5602
Source for identity of: DNAlig1 DNA-ligI