Please see the JBrowse view of Dmel\l(2)10685 for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.45
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\l(2)10685 using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
JBrowse - Visual display of RNA-Seq signals
View Dmel\l(2)10685 in JBrowse2-2
2-1.7
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Mutant alleles are recessive lethal. Although CG4749 mutant animals reach the third instar larval stage, they develop more slowly than wild type and die before pupation. In addition to developmental retardation, the mutant larvae develop melanized masses in the larval hindgut epithelium. These cells undergo autophagic programmed cell death, exhibiting an increased number and volume of autophagic vacuoles. Melanization of those affected epithelia is accompanied in most cases. Abnormal mitochondria are also observed in the large intestine epithelium.
Area matching Drosophila EST AA695104 (inverted).
Source for merge of: CG4749 anon-WO0118547.81
Source for merge of: l(2)10685 CG4749
Source for merge of l(2)10685 CG4749 was that the insertions in two alleles of the l(2)10685 complementation group (P{lacW}l(2)10685k00420 and P{PZ}l(2)1068510685) map within the CG4749 transcription unit.
Source for merge of CG4749 anon-WO0118547.81 was sequence comparison ( date:051113 ).