FB2024_03 , released June 25, 2024
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
l(3)mbt, Polr2C
FlyBase ID
FBig0000121790
Interaction Network
Interactions Browser links
l(3)mbt network
Polr2C network
esyN Network Diagram
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Protein
RNA
Selected Interactor(s)
Common Interactor(s)
Reported Interactions
FBrf0254671-5.coIP.MS
Reference
Yamamoto-Matsuda et al., 2022
Description
physical association
Assay
Collection
Source/Stage
Cell line used
OSC
Participants
Corresponds to
Reported as
Role
Note
l(3)mbt 

l(3)mbt

bait
Polr2C 

Rbp3

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Identification of l(3)mbt co-repressors was discerned by additional mass spectrometry analysis after RNAi of l(3)mbt resulting in a 4-fold reduction along with Gene Ontology categorization of DNA-binding and chromatin regulation.

(Yamamoto-Matsuda et al., 2022)

Source was of OSC cell line; bait produced from endogenous gene; prey produced from endogenous gene.

(Yamamoto-Matsuda et al., 2022)
External Crossreferences and Linkouts ( 0 )
References (1)