Ichikawa, A., Kotaki, M., Sahashi, R., Yoshioka, Y., Yamaguchi, M., Ikura, K. (2011). Targeted overexpression of Drosophila transglutaminase-B induced characteristic phenotypes in a manner similar to transglutaminase-a.  Biosci. Biotechnol. Biochem. 75(7): 1402--1404.

FBrf0214446

Research paper

The Drosophila transglutaminase gene (CG7356) encodes two transglutaminases, dTG-A and dTG-B. To understand the roles of dTG-B during the development of the fly, we examined phenotypes induced through ectopic expression of dTG-B. Overexpression of dTG-B induced rough eye and extra wing crossvein phenotypes. These phenotypes were similar to those observed in the case of targeted overexpression of dTG-A.