Tanaka, K.M., Takahashi, A., Fuse, N., Takano-Shimizu-Kouno, T. (2014). A Novel Cell Death Gene Acts to Repair Patterning Defects in Drosophila melanogaster. Genetics 197(2): 739--742.
FlyBase ID
FBrf0226736
Publication Type
Research paper
Abstract
Cell death is a mechanism utilized by organisms to eliminate excess cells during development. Here, we describe a novel regulator of caspase-independent cell death, Mabiki (Mabi), that is involved in the repair of the head patterning defects caused by extra copies of bicoid in Drosophila melanogaster. Mabiki functions together with caspase-dependent cell death mechanisms to provide robustness during development.
