UAS regulatory sequences drive expression of Act57B carrying an amino acid substitution equivalent to a M307L change in the orthologous human ACTC1 gene, a variant associated with hypertrophic cardiomyopathy. The coding sequence is tagged with GFP. (FlyBase curator comment: the mutation in the human ACTC1 gene is given as M305L in FBrf0246480, M307L is the change relative to the UniProtKB:P68032 sequence. In addition, the mutation in the Act57B gene is given as M304L in FBrf0246480, however analysis of the release 6.35 annotated gene model indicates the change to be M306L).