FB2024_03 , released June 25, 2024
Recombinant Construct: P{UAS-optoDop1R2.V2}
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General Information
Symbol
P{UAS-optoDop1R2.V2}
FlyBase ID
FBtp0167569
Feature type
transgenic_transposable_element
Component Allele(s)
Size
Expression Data
Associated insertion(s)
Molecular map
Description and Uses
Construct components
Component allele Dop1R2opto.V2.UAS
Transgenic product class
Component
Use(s)
Description

UASt sequences regulate expression of 'optoDop1R2[V2]', an engineered dopamine receptor that can be activated by light (the formation of the functional receptor also requires the presence of cis-retinal, which must be provided by feeding in Drosophila). 'optoDop1R2[V2]' is a chimeric protein that is based on the light-sensitive Btau\RHO G protein-coupled receptor (GPCR), in which Btau\RHO segments containing G protein binding sites have been exchanged for those of Dop1R2; in the V2 version of optoDop1R2, intracellular loops 2 and 3 (together with proximal transmembrane residues) and the C-terminal region have been exchanged for Dop1R2 sequence.

Sequence Data
Sequence (FB)
Associated Sequence Data
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
P{UAS-optoDop1R2.V2}
UAS-optoDop1R2V2
Secondary FlyBase IDs
    References (2)