FlyBase Aberration Report: Dmel\Df(1)KA10

General Information

Symbol

Df(1)KA10

Species

D. melanogaster

Name

FlyBase ID

FBab0000482

Feature type

chromosomal_deletion

Also Known As

KA10

Computed Breakpoints include

11A1;11A7

Features within 11A1--11A7

Sequence coordinates

Member of large scale dataset(s)

Nature of Aberration

Cytological Order

Progenitor

Mutagen

X ray

Class of aberration (relative to wild type)

chromosomal_deletion

(FlyBase, 2007)

Class of aberration (relative to progenitor)

chromosomal_deletion

(Leshko-Lindsay and Corces, 1997, Pauli et al., 1995, Perrimon et al., 1989, Konrad et al., 1988, Bolshakov and Zhimulev, 1987, Savvateeva et al., 1985, Craymer and Roy, 1980)

Breakpoints

11A1;11A7

(Perrimon et al., 1989, Savvateeva et al., 1985, Craymer and Roy, 1980)

10F11-11A2;11A6-11A9

(Bolshakov and Zhimulev, 1987)

11A2;11A7

(Konrad et al., 1988)

11A1;11A7-11A8

(Pauli et al., 1995)

11A1;11A10

(Leshko-Lindsay and Corces, 1997)

Causes alleles

Carries alleles

Transposon Insertions

Formalized genetic data

Rst(1)JH << bk1 << l(1)11Ad << bk2 << gs(1)N41

Genetic mapping information

Comments

Comments on Cytology

All limits from polytene analysis (FBrf0034402)

Sequence Crossreferences

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Gene Deletion and Duplication Data

Genes Deleted / Disrupted

Complementation Data

Completely deleted / disrupted

cac

(Kawasaki et al., 2000, Kulkarni and Hall, 1987)

(Leshko-Lindsay and Corces, 1997, Craymer and Roy, 1980)

(Konrad et al., 1998, Tearle and Nusslein-Volhard, 1987, Anderson et al., 1985)

limbo

(Martin et al., 1995)

Ten-a

(Cheng et al., 2013)

tsg

(Tearle and Nusslein-Volhard, 1987, Wieschaus et al., 1984)

Partially deleted / disrupted

Molecular Data

Completely deleted

Ten-a

(Rakovitsky et al., 2007)

tsg

(Rakovitsky et al., 2007)

Partially deleted

Genes NOT Deleted / Disrupted

Complementation Data

gs(1)N41

(Hatanaka and Okada, 1991)

LIMK1

(Savvateeva-Popova et al., 2004, Savvateeva et al., 1985)

Met

(Wilson and Fabian, 1986)

Molecular Data

Genes Duplicated

Complementation Data

Completely duplicated

Partially duplicated

Molecular Data

Completely duplicated

Partially duplicated

Genes NOT Duplicated

Complementation Data

Molecular Data

Affected Genes Inferred by Location

Related Comments

Phenotypic Data

In combination with other aberrations

NOT in combination with other aberrations

Df(1)KA10 hemizygous embryos exhibit head and thorax defects similar to tsg loss of function mutants.

With a very low penetrance, Df(1)KA10 hemizygous embryos show subtle defects in segmentation, including partial fusion of denticle band pairs in the register seen for Ten-m mutants.

(Rakovitsky et al., 2007)

10% fw¹/Df(1)KA10 female progeny have wing defects; wings are not expanded or appear stringy and have separation of the wing blades. fw^U2/Df(1)KA10 transheterozygotes have reduced viability; only 15% female progeny eclose as adults and those that survive have wing defects. fw^34e/Df(1)KA10 transheterozygotes do not produce any viable adult females, female lethal phase occurs in the pupal stages.

(Leshko-Lindsay and Corces, 1997)

Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovo^D2.

(Pauli et al., 1995)

Germ-line clones lethal (Garcia-Bellido and Robbins, 1983, Genetics 103: 235-47). duplicated ventral nerve cord in hemizygous embryos cell lethal

Stocks (2)

Bloomington

963

Df(1)KA10, sn³ m¹/FM7c

Kyoto

106145

Df(1)KA10, sn³ m¹/FM7c

Notes on Origin