FlyBase Aberration Report: Dmel\Df(3R)dsx2M

General Information

Symbol

Df(3R)dsx2M

Species

D. melanogaster

Name

Deficiency (3R) doublesex

FlyBase ID

FBab0002761

Feature type

chromosomal_deletion

Also Known As

Df(3R)dsx^Mas+R2, Df(3R)dsx^M+R2

Computed Breakpoints include

84C1-84C2;84E1

Features within 84C1--84E1

Sequence coordinates

Member of large scale dataset(s)

Nature of Aberration

Cytological Order

Progenitor

dsx^M

Mutagen

X ray

(Agnel et al., 1989)

Class of aberration (relative to wild type)

chromosomal_deletion

(FlyBase, 2007)

Class of aberration (relative to progenitor)

chromosomal_deletion

(Salzberg et al., 1997, Spackman et al., 1994, Baker et al., 1991, Agnel et al., 1989, Kerridge and Thomas-Cavallin, 1988, Cavener et al., 1986)

Breakpoints

84C1-84C2;84E1

(Cavener et al., 1986)

84C;84E1-84E2

(Kerridge and Thomas-Cavallin, 1988)

84B-84C;84E1-84E2

(Agnel et al., 1989)

84C1-84C2;84E1-84E2

(Baker et al., 1991)

[];84E1--2

(Spackman et al., 1994)

84C1-84C3;84E1

(Salzberg et al., 1997)

Causes alleles

Alh^dsx2M

(Clark et al., 2007, Perrin and Dura, 2004)

Carries alleles

Transposon Insertions

Formalized genetic data

Ta << bk1 << hat << Est-9 << bk2 << dsx

Genetic mapping information

Comments

Breakpoint(s) molecularly mapped

(Agnel et al., 1989)

Proximal (84C1-3) breakpoint estimated to be at about +26 to +27 kb, based on location of 84C1-2 breaks of T(2;3)Ta¹ at +34 kb and Df(3R)Scr² at +41 kb (Baker and Wolfner, 1988, Genes Dev. 2: 477-89)

Comments on Cytology

Left limit of break 1 from polytene analysis (FBrf0044420) Right limit of break 1 from inclusion of hat (FBrf0044420) Left limit of break 2 from inclusion of dsx (FBrf0049832) Right limit of break 2 from polytene analysis (FBrf0044420)

Sequence Crossreferences

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Gene Deletion and Duplication Data

Genes Deleted / Disrupted

Complementation Data

Completely deleted / disrupted

Alh

(Perrin and Dura, 2004)

dsx

(Agnel et al., 1989)

gfzf

(Provost et al., 2006, Cavener et al., 1986)

Gld

(Cavener et al., 1986)

hat

(Baker et al., 1991, Cavener et al., 1986)

l(3)84Cb

(Cavener et al., 1986)

l(3)84Ce

(Cavener et al., 1986)

l(3)84Da

(Baker et al., 1991)

l(3)84Db

(Baker et al., 1991)

l(3)84Dc

(Baker et al., 1991)

l(3)84Dd

(Baker et al., 1991)

lap

(Babcock et al., 2003)

Mlp84B

(Clark et al., 2007, Perrin and Dura, 2004)

(Baker et al., 1991, Agnel et al., 1989, Cavener et al., 1986)

rue

(Cavener et al., 1986)

sas

(Cavener et al., 1986)

ted

(Baker et al., 1991, Cavener et al., 1986)

α-Est5

(Cavener et al., 1986)

α-Est7

(Spackman et al., 1994)

α-Est9

(Spackman et al., 1994)

αTub84D

(Lindsley and Zimm, 1992)

Partially deleted / disrupted

dsx

(Baker et al., 1991)

Molecular Data

Completely deleted

CG10098

(Clark et al., 2007)

Elmod

(Clark et al., 2007)

Partially deleted

Alh

(Clark et al., 2007, Perrin and Dura, 2004)

Mlp84B

(Clark et al., 2007)

Genes NOT Deleted / Disrupted

Complementation Data

Alh

(Cavener et al., 1986)

CG7483

(Baker et al., 1991)

grn

(Baker et al., 1991)

l(3)84Bb

(Cavener et al., 1986)

l(3)84Bc

(Cavener et al., 1986)

l(3)84Ea

(Baker et al., 1991)

l(3)84Eb

(Baker et al., 1991)

l(3)84Ec

(Baker et al., 1991)

l(3)84Ed

(Baker et al., 1991)

l(3)84Ee

(Baker et al., 1991)

l(3)84Ef

(Baker et al., 1991)

l(3)84Eg

(Baker et al., 1991)

l(3)84Ei

(Baker et al., 1991)

l(3)84Fb

(Baker et al., 1991)

l(3)84Fc

(Baker et al., 1991)

l(3)84Fd

(Baker et al., 1991)

l(3)84Fe

(Baker et al., 1991)

l(3)84Ff

(Baker et al., 1991)

l(3)84Fg

(Baker et al., 1991)

l(3)84Fh

(Baker et al., 1991)

l(3)84Fj

(Baker et al., 1991)

l(3)84Fk

(Baker et al., 1991)

l(3)84Fl

(Baker et al., 1991)

l(3)84Fm

(Baker et al., 1991)

mab

(Cavener et al., 1986)

misn

(Salzberg et al., 1997)

puc

(Baker et al., 1991)

αTub84B

(Baker et al., 1991, Hays et al., 1989, Cavener et al., 1986)

Molecular Data

Genes Duplicated

Complementation Data

Completely duplicated

Partially duplicated

Molecular Data

Completely duplicated

Partially duplicated

Genes NOT Duplicated

Complementation Data

Molecular Data

Affected Genes Inferred by Location

Related Comments

Affects both the "roe" (roughened eye) and "rn" (rotund) functions of the rn locus.

(Baker et al., 1991, Cavener et al., 1986)

Affects the "roe" (roughened eye) function of the rn locus.

(Agnel et al., 1989)

Phenotypic Data

In combination with other aberrations

Df(3R)dsx2M/Df(3R)Scx2 is pupal lethal. Df(3R)dsx2M/Df(3R)Scx2 mutants also exhibit an apparent failure of body wall muscle contraction during puparium formation.

(Clark et al., 2007)

Inferred to overlap with: Df(3R)Scx2.

(Clark et al., 2007)

Inferred to overlap with: Df(3R)Mlp84B^P8.

(Clark et al., 2007)

NOT in combination with other aberrations

The Df(3R)dsx2M chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion).

(Mason et al., 2004)

Males fertile when in combination with αTub84B⁷.

(Hays et al., 1989)

Stocks (2)

1862

106538

Notes on Origin

Discoverer

Revertant

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms and Secondary IDs (12)

Reported As

Symbol Synonym

Df dsx[M+R2]

(Iida and Cavener, 2004)

Df(2R)dsx2M

(Salzberg et al., 1997)

Df(3R)Scx^Mas+R2

(Cavener et al., 1986)

Df(3R)dsx-M+R2

Df(3R)dsx2

(Moehring and Mackay, 2004)

Df(3R)dsx2M

(Clark and Kadrmas, 2013, Labeau-Dimenna et al., 2012, Clark et al., 2007)

Df(3R)dsx2m

(Provost et al., 2006)

Df(3R)dsx^M+R2

(Perrin and Dura, 2004, Clark, 1994, Schonbaum et al., 1992, Baker et al., 1991)

Df(3R)dsx^Mas+R2

(Spackman et al., 1994, Agnel et al., 1989, Hays et al., 1989, Kerridge and Thomas-Cavallin, 1988, Cavener et al., 1986)

Df^dsx2

(Clark et al., 2007)

dsx2M

(Clark et al., 2007)

Name Synonyms

Deficiency (3R) doublesex

Secondary FlyBase IDs

References (24)

Report Sections

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