FlyBase Aberration Report: Dmel\Df(2R)bw[VDe2L]Px[KR]

FB2024_03 , released June 25, 2024

FB2024_03 , released June 25, 2024

Aberration: Dmel\Df(2R)bw^VDe2LPx^KR

General Information

Symbol

Df(2R)bw^VDe2LPx^KR

Species

D. melanogaster

Name

FlyBase ID

FBab0005117

Feature type

inversion_derived_deficiency_plus_aneuploid

Computed Breakpoints include

Features within 59E1--60B1 (Observed cytology)

Sequence coordinates

Member of large scale dataset(s)

Nature of Aberration

Cytological Order

Progenitor

(Kania et al., 1995)

(Kania et al., 1995)

Mutagen

(Kania et al., 1995)

Class of aberration (relative to wild type)

inversion_derived_deficiency_plus_aneuploid

Class of aberration (relative to progenitor)

Breakpoints

Causes alleles

Carries alleles

Transposon Insertions

Formalized genetic data

Genetic mapping information

Comments

This deletion removes a single ribosomal protein-coding gene (though other genes are also removed).

(Marygold et al., 2007)

Comments on Cytology

Distal breakpoint revised from 60D1 to 60B1 because earlier estimates were inconsistent with the data; 60B1 is a better fit.

(Cook, 2015.12.23)

Sequence Crossreferences

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Gene Deletion and Duplication Data

Genes Deleted / Disrupted

Complementation Data

Completely deleted / disrupted

(Beaton, 1997.12.27, BDGP Project Members, 1994-1999)

(Spradling et al., 1999, Beaton, 1997.12.27, BDGP Project Members, 1994-1999)

(Spradling et al., 1999, Beaton, 1997.12.27, BDGP Project Members, 1994-1999)

(BDGP Project Members, 1994-1999)

(Spradling et al., 1999, Beaton, 1997.12.27)

(Kania et al., 1995)

(Spradling et al., 1999, Beaton, 1997.12.27, BDGP Project Members, 1994-1999)

(Kahsai et al., 2016, BDGP Project Members, 1994-1999)

(Spradling et al., 1999, Beaton, 1997.12.27)

(Spradling et al., 1999, Beaton, 1997.12.27, Kania et al., 1995)

(Spradling et al., 1999, Beaton, 1997.12.27, BDGP Project Members, 1994-1999)

(Spradling et al., 1999, Beaton, 1997.12.27)

(Spradling et al., 1999, Beaton, 1997.12.27)

(Beaton, 1997.12.27, BDGP Project Members, 1994-1999)

Partially deleted / disrupted

Molecular Data

Completely deleted

(Marygold et al., 2007)

Partially deleted

Genes NOT Deleted / Disrupted

Complementation Data

(Spradling et al., 1999, Beaton, 1997.12.27, BDGP Project Members, 1994-1999)

(Beaton, 1997.12.27)

(Edgar et al., 2005)

(Beaton, 1997.12.27, BDGP Project Members, 1994-1999)

(BDGP Project Members, 1994-1999)

(Spradling et al., 1999, Beaton, 1997.12.27, BDGP Project Members, 1994-1999)

(Spradling et al., 1999, Beaton, 1997.12.27)

(Spradling et al., 1999, Beaton, 1997.12.27, BDGP Project Members, 1994-1999)

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

(Spradling et al., 1999, Beaton, 1997.12.27)

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

(Spradling et al., 1999, Beaton, 1997.12.27, BDGP Project Members, 1994-1999)

(Spradling et al., 1999, Beaton, 1997.12.27)

(BDGP Project Members, 1994-1999)

(BDGP Project Members, 1994-1999)

(BDGP Project Members, 1994-1999)

(Spradling et al., 1999)

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

(Spradling et al., 1999)

(Spradling et al., 1999)

(Spradling et al., 1999, Beaton, 1997.12.27)

(Spradling et al., 1999, Beaton, 1997.12.27)

(BDGP Project Members, 1994-1999)

(Spradling et al., 1999)

(Spradling et al., 1999)

(Spradling et al., 1999, Beaton, 1997.12.27)

(Spradling et al., 1999, Beaton, 1997.12.27, BDGP Project Members, 1994-1999)

(Spradling et al., 1999, Beaton, 1997.12.27, BDGP Project Members, 1994-1999)

Molecular Data

Genes Duplicated

Complementation Data

Completely duplicated

Partially duplicated

Molecular Data

Completely duplicated

Partially duplicated

Genes NOT Duplicated

Complementation Data

Molecular Data

Affected Genes Inferred by Location (0)

If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
In this case, the "Export to Hitlist" button at left will also be disabled.

Related Comments

Phenotypic Data

In combination with other aberrations

Lethal in combination with Df(2R)BSC652.

(Kahsai et al., 2016)

NOT in combination with other aberrations

Flies heterozygous for the deletion do not show a Minute bristle phenotype.

(Marygold et al., 2007)

The Df(2R)bw^VDe2LPx^KR chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion).

(Mason et al., 2004)

Intermediate second site non-complementing phenotype with zip^Ebr and zip^mhc-c6.1 : malformed phenotype penetrance 25-75%. Shows a dominant wing blister phenotype.

(Halsell and Kiehart, 1998)

Stocks (2)

1587

Df(2R)bw^VDe2LPx^KR/In(2LR)Gla, wg^Gla-1

106403

Df(2R)bw^VDe2LPx^KR/In(2LR)Gla

Notes on Origin

Discoverer

Kaufman.

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Designation as "In(2R)bw^VDe2LCy^R" was in error.

(BDGP Project Members, 1994-1999)

Synonyms and Secondary IDs (8)

Reported As

Symbol Synonym

BL-1587

(Edgar et al., 2005)

Df(2R)bw^VDe2LPx^KR

(Kahsai et al., 2016, Cook, 2015.12.23)

Df(2R)bw^VDe2LPx^Kr

(Halsell and Kiehart, 1998)

In(2R)bw^VDe2L

(Kania et al., 1995)

In(2R)bw^VDe2LCy^R

(BDGP Project Members, 1994-1999)

In(2R)bw^VDe2LPx^KR

In(2R)bw^VDe2LPx^Kr

(Spradling et al., 1999)

In(2R)bwVDe2LPxKR

(Beaton, 1997.12.27)

Name Synonyms

Secondary FlyBase IDs

FBab0005118

References (11)

Report Sections