FlyBase Allele Report: Dmel\kni[9]

General Information

Symbol

Dmel\kni⁹

Species

D. melanogaster

Name

FlyBase ID

FBal0005779

Feature type

allele

Associated gene

Dmel\kni

Associated Insertion(s)

Carried in Construct

Also Known As

kni^IL26

Key Links

Allele class

loss of function allele

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

loss of function allele

(Nibu et al., 1998)

Mutagen

ethyl methanesulfonate

(Tearle and Nusslein-Volhard, 1987)

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

Wing vein L2 forms normally in homozygous clones which cover vein L2 on both the dorsal and ventral wing surfaces.

(Lunde et al., 1998)

strong

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhancer of

Statement

Reference

kni⁹ is a non-enhancer of lethal | embryonic stage | maternal effect phenotype of Gug^unspecified

(Zhang et al., 2002)

Phenotype Manifest In

Enhanced by

Statement

Reference

kni⁹ has phenotype, enhanceable by gro^E48

(Payankaulam and Arnosti, 2009)

kni⁹ has phenotype, enhanceable by gro¹

(Payankaulam and Arnosti, 2009)

Enhancer of

Statement

Reference

kni⁹ is an enhancer of phenotype of gro^E48

(Payankaulam and Arnosti, 2009)

kni⁹ is an enhancer of phenotype of gro¹

(Payankaulam and Arnosti, 2009)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

kni⁹ fails to complement kni^ri-1 when it is carried on a chromosome such as TM3 or In(3LR)LD6 that is rearranged with respect to the kni⁹ mutant chromosome. kni⁹ fully complements kni^ri-1 when the kni^ri-1 and kni⁹ alleles are carried on non-rearranged chromosomes.