FlyBase Allele Report: Dmel\rept[06945]

General Information

Symbol

Dmel\rept⁰⁶⁹⁴⁵

Species

D. melanogaster

Name

FlyBase ID

FBal0009584

Feature type

allele

Associated gene

Dmel\rept

Associated Insertion(s)

P{PZ}rept⁰⁶⁹⁴⁵

Carried in Construct

Also Known As

l(3)06945

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

Progenitor genotype

Associated Insertion(s)

P{PZ}rept⁰⁶⁹⁴⁵

Cytology

Description

Insertion in the 5' UTR, 17 nucleotides upstream of the ATG codon.

(Qi et al., 2006)

Allele components

Component

Use(s)

Inserted element

P{PZ}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3L:19,255,497..19,255,497 [-]

(Qi et al., 2006, Bauer et al., 2000, Spradling et al., 1999, BDGP Project Members, 1994-1999)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

Heterozygous males do not have ectopic sex combs on the second and third legs.

Females containing homozygous germline clones do not produce embryos.

(Qi et al., 2006)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

rept[+]/rept⁰⁶⁹⁴⁵ is an enhancer of visible phenotype of ph-p⁴¹⁰

(Qi et al., 2006)

rept[+]/rept⁰⁶⁹⁴⁵ is an enhancer of visible | dominant phenotype of Pcl¹¹

(Qi et al., 2006)

Suppressor of

Statement

Reference

rept[+]/rept⁰⁶⁹⁴⁵ is a suppressor of visible | heat sensitive phenotype of peb¹

(Wilk et al., 2004)

rept[+]/rept⁰⁶⁹⁴⁵ is a suppressor of visible | dominant phenotype of Kr^If-1

(Carrera et al., 1998)

Other

Statement

Reference

Pc[+]/Pc¹¹, rept⁰⁶⁹⁴⁵ has visible | dominant phenotype

(Qi et al., 2006)

Phenotype Manifest In

Enhancer of

Statement

Reference

rept[+]/rept⁰⁶⁹⁴⁵ is an enhancer of mesothoracic leg & sex comb | ectopic phenotype of ph-p⁴¹⁰

(Qi et al., 2006)

rept[+]/rept⁰⁶⁹⁴⁵ is an enhancer of mesothoracic leg & sex comb | ectopic phenotype of Pcl¹¹

(Qi et al., 2006)

Suppressor of

Statement

Reference

rept[+]/rept⁰⁶⁹⁴⁵ is a suppressor of eye | heat sensitive phenotype of peb¹

(Wilk et al., 2004)

rept[+]/rept⁰⁶⁹⁴⁵ is a suppressor of eye phenotype of Kr^If-1

(Carrera et al., 1998)

Other

Statement

Reference

Pcl¹¹, rept[+]/rept⁰⁶⁹⁴⁵ has metathoracic leg & sex comb | ectopic phenotype

(Qi et al., 2006)

ph-p⁴¹⁰, rept[+]/rept⁰⁶⁹⁴⁵ has metathoracic leg & sex comb | ectopic phenotype

(Qi et al., 2006)

Pc[+]/Pc¹¹, rept⁰⁶⁹⁴⁵ has mesothoracic leg & sex comb | ectopic phenotype

(Qi et al., 2006)

Pc[+]/Pc¹¹, rept⁰⁶⁹⁴⁵ has metathoracic leg & sex comb | ectopic phenotype

(Qi et al., 2006)

Additional Comments

Genetic Interactions

Statement

Reference

rept⁰⁶⁹⁴⁵/+ enhances the Df(3L)Pc/+ phenotype; the frequency of second and third legs having an ectopic sex comb is increased (to 41% and 25% respectively) in the double heterozygous males.

rept⁰⁶⁹⁴⁵ does not show an ectopic sex comb phenotype in either the second or third legs in double heterozygous combination with either esc¹ or Psc^k07834.

47% of rept⁰⁶⁹⁴⁵/+ ; Pcl¹¹/+ males have ectopic sex combs on the second leg and 4% have ectopic sex combs on the third leg.

rept⁰⁶⁹⁴⁵ Pc¹¹ double heterozygous males have ectopic sex combs on the second and third legs (47% and 5% of flies respectively).

rept⁰⁶⁹⁴⁵ Psc¹ double heterozygous males have ectopic sex combs on the second and third legs (40% and 2% of flies respectively).

rept⁰⁶⁹⁴⁵ shows little or no interaction (in terms of ectopic sex comb phenotype) when in double heterozygous combination with one of Psc^vgD, esc²¹ or Pcl⁷.

rept⁰⁶⁹⁴⁵/+ enhances the ph-p⁴¹⁰/Y ectopic sex comb phenotype; 100% of the double mutant flies have ectopic sex combs on both the second and third legs.

(Qi et al., 2006)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

rept⁰⁶⁹⁴⁵ is rescued by Scer\GAL4^Act5C.PU/rept^UASp.cQa

(Qi et al., 2006)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

11706

P{PZ}rept⁰⁶⁹⁴⁵ ry⁵⁰⁶/TM3, ry^RK Sb¹ Ser¹

Notes on Origin

Discoverer

A. Spradling.

Comments

Complements: l(3)neo27¹.

(BDGP Project Members, 1994-1999)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (6)

Reported As

Symbol Synonym

P1706

(Bauer et al., 2000)

Reptin⁰⁶⁹⁴⁵

(Flegel et al., 2016)

l(3)06945

(Spradling et al., 1999, Carrera et al., 1998)

l(3)06945⁰⁶⁹⁴⁵

(BDGP Project Members, 1994-1999)

rept⁰⁶⁹⁴⁵

(Ihry and Bashirullah, 2014)

rept^l(3)06945

(Qi et al., 2006)

Name Synonyms

Secondary FlyBase IDs

References (10)

Report Sections

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