Inserted opus transposable element gives a four base-pair (TGTA) duplication in the intron between exon III and exon IV.
Retrotransposon insertion into cistron B.
lz34 adults have a severe mutant eye phenotype. Ectopic cell death is seen in third larval instar eye discs.
Rough eye phenotype. Some secondary pigment cells are absent. Photoreceptor neuron recruitment is perturbed. Some facets have only six cells, R7 appears to be transformed to R1-6-like photoreceptor cell. An R7-like cell is missing in some facets.
Homozygotes show disruption of the ommatidial array and fusion of ommatidia across the posterior half of the eye. Black pock marks are visible on the surface of the eye. The retina is moderately disorganised, particularly in the posterior region. The underlying lamina is also disorganised in the posterior region. The fenestrated membrane is abnormal. Rhabdomeric bundles are found in the cortex of the lamina. The number and type of photoreceptors in each ommatidium are sometimes abnormal. lz50e/lz34 females have a thin, vertical, central stripe of black pock marks in an otherwise normal eye.
R7 cells are converted to outer receptor cells.
Displays locomotor activity rhythm with an approximately 24h period.
The antennal funiculus is reduced in size in hemizygous males. All large and small basiconic sensilla on the antennal funiculus are missing, and the number of trichoid sensilla on the antennal funiculus is reduced. The number of coeloconic sensilla on the antennal funiculus is normal.
Homozygotes have rough eyes which are reduced in size. Red eye pigment is distributed over the entire eye. The tarsal claws are reduced. The spermathecae and pars ovariae are absent in homozygous females.
Eye phenotype intermediate between lz and lz3. Surface of eye has large areas of fused facets with a few normal facets (Clayton, 1957); eye color dark red with small yellowish spots. Larval Malpighian tubes slightly lighter than normal; variable (Brehme and Demerec, 1942). Tarsal claws reduced. Spermathecae and parovaria absent from homozygous females, which accumulate stage 14 oocyte and are quite infertile; some lz34/+ females have abnormal parovaria (Anderson, 1945). Eye effect, but not other aspects of phenotype, enhanced by svspa-e(lz); eye converted from a glossy to a spectacle phenotype (Beeson and Bender, 1975). In the presence of su(lz34), lz34 flies have virtually normal eyes. Beeson and Bender were unable to confirm previous observations of Bender and Green (1960) that su(lz34) increases the fecundity of lz34 females. Unaffected by su(f)6 (Schalet) or su(Hw)2; however suppressed by su(pr) and enhanced by su(s) and su(wa) (Rutledge, Mortin, Schwarz, Thierry-Mieg and Meselson, 1988). RK1. glossy; tarsal structures reduced or absent; spermathecae absent; parovaria absent female-sterile
lz34 has increased cell death phenotype, suppressible by su(lz34)1
lz34 is a suppressor of macrochaeta | ectopic & antenna phenotype of amos1/Df(2L)M36F-S6
Beadle, 22nd Nov. 1934.
lz34 maps to the spectacle sublocus of lz.