FlyBase Allele Report: Dmel\rn[16]

General Information

Symbol

Dmel\rn¹⁶

Species

D. melanogaster

Name

FlyBase ID

FBal0014619

Feature type

allele

Associated gene

Dmel\rn

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

diepoxybutane

Nature of the Allele

Allele class

Mutagen

diepoxybutane

(Agnel et al., 1989)

Progenitor genotype

Caused by aberration

Df(3R)rn¹⁶

Cytology

Polytene chromosomes normal.

(Agnel et al., 1989)

Description

Approximately 1 kb deletion between -6.5 and -2.1 kb (coordinates relative to the distal breakpoint of Df(3R)Scx4).

(Agnel et al., 1989)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

sterile

(Agnel et al., 1989)

visible (with Df(3R)rn20)

(St Pierre et al., 2002)

Phenotype Manifest In

antenna

(Agnel et al., 1989)

egg chamber

(Agnel et al., 1989)

eye

(Agnel et al., 1989)

eye (with Df(3R)rn20)

(St Pierre et al., 2002)

eye disc (with Df(3R)rn20)

(St Pierre et al., 2002)

eye disc morphogenetic furrow (with Df(3R)rn20)

(St Pierre et al., 2002)

eye photoreceptor cell (with Df(3R)rn20)

(St Pierre et al., 2002)

haltere

(Agnel et al., 1989)

leg | distal

(Agnel et al., 1989)

metatarsus (with Df(3R)rn20)

(St Pierre et al., 2002)

oocyte

(Agnel et al., 1989)

ovary

(Agnel et al., 1989)

pretarsus (with Df(3R)rn20)

(St Pierre et al., 2002)

proboscis

(Agnel et al., 1989)

sex comb

(Agnel et al., 1989)

sex comb (with Df(3R)rn20)

(St Pierre et al., 2002)

tarsal segment 2 (with Df(3R)rn20)

(St Pierre et al., 2002)

tarsal segment 3 (with Df(3R)rn20)

(St Pierre et al., 2002)

tarsal segment 4 (with Df(3R)rn20)

(St Pierre et al., 2002)

wing | proximal

(Agnel et al., 1989)

Detailed Description

Statement

Reference

rn¹⁶/rn^roe-3 adult eyes show a moderate small and rough eye phenotype.

(Melicharek et al., 2008)

rn¹⁶ shows both "rn" and "roe" phenotypes. rn¹⁶/Df(3R)rn20 males lack the sex comb and all five tarsi of the leg appear fused into one segment. The claw is still present. rn¹⁶/Df(3R)rn20 animals have small, rough eyes. There are an average of 5.7 photoreceptors per ommatidium in these flies. Larval eye imaginal discs show abnormal photoreceptor differentiation. The morphogenetic furrow appears to progress more slowly across the disc in some areas than others, creating a wave-like appearance of developing photoreceptor clusters near the morphogenetic furrow.

(St Pierre et al., 2002)

Allele shows both rotund and roughened eye phenotypes.

(Agnel et al., 1989)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement