FlyBase Allele Report: Dmel\sc[5]

General Information

Symbol

Dmel\sc⁵

Species

D. melanogaster

Name

FlyBase ID

FBal0015194

Feature type

allele

Associated gene

Dmel\sc

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

X ray

Nature of the Allele

Allele class

Mutagen

X ray

(Lindsley and Zimm, 1992)

Progenitor genotype

Cytology

Description

Deletion in the sc regulatory region.

(Gause et al., 1996)

1.2 kb deletion around -17;. 0 defined as the more distal EcoRI site within the sc^S2 molecular deficiency.

(Lindsley and Zimm, 1992)

1.3kb deletion.

(Campuzano et al., 1985)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

viable

(Golovnin et al., 2003)

visible

(Golovnin et al., 2003)

Phenotype Manifest In

abdominal sternite bristle

(Lindsley and Zimm, 1992)

scutellar bristle

(Golovnin et al., 2003, Lindsley and Zimm, 1992)

Detailed Description

Statement

Reference

sc⁵ mutant adults do not display changes in the number of scutellar bristles, as compared to controls.

(Xu et al., 2019)

Mutants show loss of the scutellar bristle. Bristle pigmentation is normal.

(Golovnin et al., 2003)

Sternital and scutellar bristles reduced in number; others rarely affected. sc⁵/sc⁶ is practically wild type. RK1.

(Lindsley and Zimm, 1992)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

sc⁵ has visible phenotype, enhanceable by mod(mdg4)^ul/mod(mdg4)^ul

(Golovnin et al., 2003)

sc⁵ has visible phenotype, enhanceable by su(Hw)⁷/su(Hw)^V

(Golovnin et al., 2003)

Suppressor of

Statement

Reference

sc[+]/sc⁵ is a suppressor of visible | dominant | adult stage phenotype of lncRNA:SMRG^M

(Xu et al., 2019)

sc[+]/sc⁵ is a suppressor of visible | dominant | adult stage phenotype of E(spl)mβ-HLH^12-11

(Xu et al., 2019)

Other

Statement

Reference

mod(mdg4)^ul, sc⁵ has viable phenotype

(Golovnin et al., 2003)

sc⁵, su(Hw)⁷/su(Hw)^V has viable phenotype

(Golovnin et al., 2003)

Df(1)260-1, sc⁵ has visible phenotype

(Mari-Beffa et al., 1991)

Df(1)sc19, sc⁵ has visible phenotype

(Mari-Beffa et al., 1991)

Phenotype Manifest In

Enhanced by

Statement

Reference

sc⁵ has scutellar bristle phenotype, enhanceable by mod(mdg4)^ul/mod(mdg4)^ul

(Golovnin et al., 2003)

sc⁵ has scutellar bristle phenotype, enhanceable by su(Hw)⁷/su(Hw)^V

(Golovnin et al., 2003)

NOT suppressed by

Statement

Reference

sc⁵ has phenotype, non-suppressible by su(Hw)²

(Lindsley and Grell, 1968)

Other

Statement

Reference

sc⁵, su(Hw)⁷/su(Hw)^V has ocellar bristle phenotype

(Golovnin et al., 2003)

sc⁵, su(Hw)⁷/su(Hw)^V has anterior orbital bristle phenotype

(Golovnin et al., 2003)

sc⁵, su(Hw)⁷/su(Hw)^V has anterior supraalar bristle phenotype

(Golovnin et al., 2003)

sc⁵, su(Hw)⁷/su(Hw)^V has postocellar bristle phenotype

(Golovnin et al., 2003)

Df(1)260-1, sc⁵ has tergite phenotype

(Mari-Beffa et al., 1991)

Df(1)260-1, sc⁵ has chaeta phenotype

(Mari-Beffa et al., 1991)

Df(1)sc19, sc⁵ has tergite phenotype

(Mari-Beffa et al., 1991)

Df(1)sc19, sc⁵ has chaeta phenotype

(Mari-Beffa et al., 1991)

Additional Comments

Genetic Interactions

Statement

Reference

sc⁵ ; su(Hw)^V/su(Hw)⁷ animals show loss of a number of bristles. Bristle pigmentation is normal in these animals. Bristle pigmentation is normal in sc⁵ ; mod(mdg4)^ul/mod(mdg4)^ul animals.

(Golovnin et al., 2003)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (1)

Holtzman, S. and Kaufman, T. (2013)

Mutant

Wild-type

Stocks (4)

Bloomington

178

y¹ sc⁵

735

Df(1)w258-48, y¹ sc⁵ N^spl-1/C(1)DX, y¹ f¹; Dp(1;3)w^vco/+

Kyoto

101185

sc⁵

106053

Df(1)w258-48, y¹ sc⁵ N^spl-1/C(1)DX, y¹ f¹; Dp(1;3)w^vco/+

Notes on Origin

Discoverer

Induced on: y^unspecified.

(Lindsley and Zimm, 1992)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

sc⁵

(Xu et al., 2019, Mari-Beffa et al., 1991)

Name Synonyms

Secondary FlyBase IDs

References (12)

Report Sections

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