FlyBase Allele Report: Dmel\Ets97D[tne-1]

General Information

Symbol

Dmel\Ets97D^tne-1

Species

D. melanogaster

Name

FlyBase ID

FBal0016901

Feature type

allele

Associated gene

Dmel\Ets97D

Associated Insertion(s)

Carried in Construct

Also Known As

tne

Key Links

Allele class

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

Mutagen

ethyl methanesulfonate

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

female sterile | recessive

(Schulz et al., 1993)

viable

(Schulz et al., 1993)

Phenotype Manifest In

abdominal segment 2

(Schulz et al., 1993)

abdominal segment 3

(Schulz et al., 1993)

abdominal segment 4

(Schulz et al., 1993)

abdominal segment 5

(Schulz et al., 1993)

abdominal segment 6

(Schulz et al., 1993)

abdominal segment 7

(Schulz et al., 1993)

border follicle cell

(Gajewski and Schulz, 1995)

egg

(Gajewski and Schulz, 1995, Schulz et al., 1993)

egg chorion

(Schulz et al., 1993)

follicle cell

(Schulz et al., 1993)

mitochondrion | somatic clone | third instar larval stage

(Baltzer et al., 2009)

nurse cell & nuclear chromosome

(Schulz et al., 1993)

Detailed Description

Statement

Reference

Mitochondrial abundance is reduced in homozygous Ets97D^tne-1 mutant fat body clones

(Baltzer et al., 2009)

Eggs laid by hemizygous Ets97D^tne-1 females do not show any embryonic development. The eggshells show a wide range of ventralised phenotypes. The border follicle cells fail to migrate in Ets97D^tne-1/Df(3R)ro80b egg chambers.

(Gajewski and Schulz, 1995)

Ets97D^tne-1 is viable but female sterile in transheterozygous combination with Ets97D⁶¹³, Ets97D⁹⁰² or Df(3R)ro80b. Ets97D^tne-1/Df(3R)ro80b and Ets97D^tne-1/Ets97D⁶¹³ females show abnormalities in oogenesis, including problems with nurse cell chromosome decondensation, follicle cell migration and chorion formation. Eggs obtained from these females show no obvious development. Ets97D^tne-1/Ets97D⁹⁰² females have some abnormalities in oogenesis, although the majority of eggs laid by these females appear morphologically normal. Approximately 15% of these eggs develop to late stage embryos, a small percent of these hatch into first instar larvae and in rare cases some animals develop to the adult stage. The embryos have defects in abdominal segmentation, ranging from mild defects in segments A4 to A7, to broad fusion and/or deletion of segments including A2 to A7.

(Schulz et al., 1993)

female-sterile. Very small eggs.

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Ets97D^tne-1 is a suppressor of increased cell size | somatic clone phenotype of Cdk4^UAS.cMa, CycD^UAS.cDa, Scer\GAL4^αTub84B.PP

(Baltzer et al., 2009)

Other

Statement

Reference

Ets97D^tne-1/Df(3R)ro80b, slbo⁰¹³¹⁰/slbo[+] has decreased fecundity | female phenotype

(Gajewski and Schulz, 1995)

Ets97D^tne-1/Df(3R)ro80b, capu[+]/capu¹ has decreased fecundity | female phenotype

(Gajewski and Schulz, 1995)

Ets97D^tne-1/Df(3R)ro80b, capu[+]/capu^HK3 has decreased fecundity | female phenotype

(Gajewski and Schulz, 1995)

Phenotype Manifest In

Enhanced by

Statement

Reference

Ets97D^tne-1 has egg phenotype, enhanceable by capu[+]/capu^HK3

(Gajewski and Schulz, 1995)

Ets97D^tne-1 has egg phenotype, enhanceable by capu[+]/capu¹

(Gajewski and Schulz, 1995)

Suppressor of

Statement

Reference

Ets97D^tne-1 is a suppressor of fat body | somatic clone phenotype of Cdk4^UAS.cMa, CycD^UAS.cDa, Scer\GAL4^αTub84B.PP

(Baltzer et al., 2009)

Ets97D^tne-1 is a suppressor of mitochondrion | somatic clone phenotype of Cdk4^UAS.cMa, CycD^UAS.cDa, Scer\GAL4^αTub84B.PP

(Baltzer et al., 2009)

Other

Statement

Reference

Ets97D^tne-1, slbo⁰¹³¹⁰ has ovary phenotype

(Gajewski and Schulz, 1995)

Additional Comments

Genetic Interactions

Statement

Reference

Homozygous Ets97D^tne-1 suppresses the increase in cell size seen in fat body clones co-expressing CycD^Scer\UAS.cDa and Cdk4^Scer\UAS.cMa under the control of Scer\GAL4^αTub84B.PP. The increases in the amount of mitochondria in the cytoplasm and COX activity are also suppressed.

(Baltzer et al., 2009)

slbo⁰¹³¹⁰/+ ; Ets97D^tne-1/Df(3R)ro80b females do not lay any eggs. The ovaries of these flies contain fewer egg chambers that have developed to stage 9 and beyond compared to those of control +/+ ; slbo⁰¹³¹⁰/+ ; Ets97D^tne-1/Df(3R)ro80b flies. spir^PJ56 does not interact with Ets97D^tne-1. One copy of capu^HK3 or capu¹ decreases the number of eggs laid by Ets97D^tne-1/Df(3R)ro80b females.

(Gajewski and Schulz, 1995)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Ets97D^tne-1

delg^tne

(Baltzer et al., 2009)

tne

(Gajewski and Schulz, 1995, Gajewski and Schulz, 1995, Schulz et al., 1993)

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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