FB2024_03 , released June 25, 2024
Allele: Dmel\wbSF11
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General Information
Symbol
Dmel\wbSF11
Species
D. melanogaster
Name
FlyBase ID
FBal0018471
Feature type
allele
Associated gene
Dmel\wb
Associated Insertion(s)
Carried in Construct
Also Known As
l(2)br1SF11
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
triethylenemelamine
(Ashburner et al., 1999.10.12, Woodruff and Ashburner, 1979)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      wb[+]/wbSF11 is an enhancer of visible | heat sensitive phenotype of Dcr-2UAS.cDa, EogtGD5084, Scer\GAL4en.PU

      (Müller et al., 2013)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      wb[+]/wbSF11 is an enhancer of wing blade posterior compartment | heat sensitive phenotype of Dcr-2UAS.cDa, EogtGD5084, Scer\GAL4en.PU

      (Müller et al., 2013)

      wb[+]/wbSF11 is an enhancer of heart primordium phenotype of sli2

      (MacMullin and Jacobs, 2006)
      Other
      Statement
      Reference

      scb2/scb[+], wbSF11 has embryonic heart cardioblast phenotype

      (Vanderploeg et al., 2012)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The wing blistering phenotype seen in the posterior compartment of wings in flies expressing EogtGD5084 under the control of Scer\GAL4en.PU in the presence of Dcr-2Scer\UAS.cDa is enhanced if the flies are also heterozygous for wbSF11.

      (Müller et al., 2013)

      wbSF11/scb2 double heterozygous embryos show defects in alignment of the cardioblasts at the dorsal midline.

      (Vanderploeg et al., 2012)

      wbSF11/+, sli2/+ embryos show heart defects that include contralaterally placed cardial cell nuclei, rows of migrating cardial cells that are missing cells and laterally placed cardial cells.

      (MacMullin and Jacobs, 2006)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer

      Woodruff.

      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      l(2)br1SF11
      (Ashburner et al., 1982, Woodruff and Ashburner, 1979)
      wbSF11,9437
      (MacMullin and Jacobs, 2006)
      wbSF11
      (Müller et al., 2013, Vanderploeg et al., 2012)
      Name Synonyms
      Secondary FlyBase IDs
        References (7)