FB2024_03 , released June 25, 2024
Allele: Dmel\ptc18
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General Information
Symbol
Dmel\ptc18
Species
D. melanogaster
Name
FlyBase ID
FBal0028508
Feature type
allele
Associated gene
Dmel\ptc
Associated Insertion(s)
Carried in Construct
Also Known As
ptcP78
Key Links
Allele class

amorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - genetic evidence

(Chen and Struhl, 1996, Cadigan et al., 1994)
Mutagen
PM hybrid dysgenesis
(Phillips et al., 1990, Nakano et al., 1989)
Progenitor genotype
Cytology
Description

Deletion of 15kb.

(Nakano et al., 1989)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      ptc mutant embryos lack sensory organs (M. Ruiz-Gomez and A. Ghysen).

      (Capdevila et al., 1994)

      homozygous lethal

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      ptcS2/ptc18 is rescued by ptcαTub84B.PCa

      (Chen and Struhl, 1996)
      Comments

      ptcαTub84B.PCa can rescue ptc18/ptcS2 mutants to adulthood, adults have normal wings.

      (Chen and Struhl, 1996)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Not associated with a P-element insertion.

      P-element insertion at cytological location 44D3-44D4 is not associated with the mutant phenotype.

      (Nakano et al., 1989)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      References (8)