FB2024_03 , released June 25, 2024
Allele: Dmel\RasGAP1B1
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General Information
Symbol
Dmel\RasGAP1B1
Species
D. melanogaster
Name
FlyBase ID
FBal0029794
Feature type
allele
Associated gene
Dmel\RasGAP1
Associated Insertion(s)
Carried in Construct
Also Known As
rI533B1
Key Links
Allele class

amorphic allele - genetic evidence

Mutagen
    Nature of the Allele
    Allele class

    amorphic allele - genetic evidence

    (Gaul et al., 1992)
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Gap1B1 homozygous clones in the dorsal air sac primordium are found at the tip of the primordium at a significantly lower frequency than wild-type clones.

        (Cabernard and Affolter, 2005)

        Clones in the wing intervein regions that are doubly mutant for Gap1B1 and emc1 largely differentiate as veins.

        (Baonza and Garcia-Bellido, 1999)

        Disrupted eye development. PACAP38 (neuropeptide pituitary adenylyl cyclase-activating polypeptide) induced normal enhancement of K+ currents.

        (Guo et al., 1997)

        Rough eye phenotype.

        (Gaul et al., 1992)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Suppressor of
        Statement
        Reference

        RasGAP1B1 is a suppressor of visible phenotype of CanBGMR.PS, Pp2B-14Dact.GMR

        (Sullivan and Rubin, 2002)

        RasGAP1B1 is a suppressor of visible phenotype of Pp2B-14Dact.GMR

        (Sullivan and Rubin, 2002)
        Phenotype Manifest In
        Suppressor of
        Statement
        Reference

        RasGAP1B1 is a suppressor of eye phenotype of CanBGMR.PS, Pp2B-14Dact.GMR

        (Sullivan and Rubin, 2002)

        RasGAP1B1 is a suppressor of eye phenotype of Pp2B-14Dact.GMR

        (Sullivan and Rubin, 2002)

        RasGAP1B1 is a suppressor of photoreceptor cell R7 phenotype of boss1

        (Gaul et al., 1992)

        RasGAP1B1 is a suppressor of photoreceptor cell R7 phenotype of sev14

        (Gaul et al., 1992)
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (5)
        Reported As
        Symbol Synonym
        Gap1B1
        RasGAP1B1
        gap1B1
        (Cabernard and Affolter, 2005)
        rI533B1
        (Zhong, 1995, Gaul et al., 1992)
        rI533B1
        (Guo et al., 1997)
        Name Synonyms
        Secondary FlyBase IDs
          References (7)